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Olivi, Lorenzo (author), Berger, Mareike (author), Creyghton, Ramon N.P. (author), De Franceschi, N. (author), Dekker, C. (author), Mulder, Bela M. (author), Claassens, Nico J. (author), ten Wolde, Pieter Rein (author), van der Oost, John (author)
Recent developments in synthetic biology may bring the bottom-up generation of a synthetic cell within reach. A key feature of a living synthetic cell is a functional cell cycle, in which DNA replication and segregation as well as cell growth and division are well integrated. Here, we describe different approaches to recreate these processes...
review 2021