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Chataigner, Lucas M.P. (author), Gogou, C. (author), den Boer, Maurits A. (author), Pereira Frias, C.S. (author), Thies-Weesie, Dominique M.E. (author), Granneman, Joke C.M. (author), Heck, Albert J.R. (author), Meijer, D.H.M. (author), Janssen, Bert J.C. (author)
Cell-surface expressed contactin 1 and neurofascin 155 control wiring of the nervous system and interact across cells to form and maintain paranodal myelin-axon junctions. The molecular mechanism of contactin 1 – neurofascin 155 adhesion complex formation is unresolved. Crystallographic structures of complexed and individual contactin 1 and...
journal article 2022
document
Wentinck, Koen (author), Gogou, C. (author), Meijer, D.H.M. (author)
Significant advances in the past decade have enabled high-resolution structure determination of a vast variety of proteins by cryogenic electron microscopy single particle analysis. Despite improved sample preparation, next-generation imaging hardware, and advanced single particle analysis algorithms, small proteins remain elusive for...
review 2022