Engineered biochemical cues of regenerative biomaterials to enhance endogenous stem/progenitor cells (ESPCs)-mediated articular cartilage repair

As a highly specialized shock-absorbing connective tissue, articular cartilage (AC) has very limited self-repair capacity after traumatic injuries, posing a heavy socioeconomic burden. Common clinical therapies for small- to medium-size focal AC defects are well-developed endogenous repair and cell-based strategies, including microfracture,...

Direct microbial electron uptake as a mechanism for stainless steel corrosion in aerobic environments

Shewanella oneidensis MR-1 is an attractive model microbe for elucidating the biofilm-metal interactions that contribute to the billions of dollars in corrosion damage to industrial applications each year. Multiple mechanisms for S. oneidensis-enhanced corrosion have been proposed, but none of these mechanisms have previously been rigorously...

Guanidium-assisted crystallization engineering for highly efficient CsPbI₃ solar cells

Iodine vacancies and uncoordinated iodide ions of CsPbI₃ films are mainly responsible for nonradiative recombination. Here, we report a composition-engineering passivation method that through guanidium (GA⁺) and I⁻ forms strong hydrogen bonds to passivate iodine vacancies and reduce defects. Both experimental...

Functionalized Hydrogels for Articular Cartilage Tissue Engineering

Articular cartilage (AC) is an avascular and flexible connective tissue located on the bone surface in the diarthrodial joints. AC defects are common in the knees of young and physically active individuals. Because of the lack of suitable tissue-engineered artificial matrices, current therapies for AC defects, especially full-thickness AC...

New innovations in pavement materials and engineering: A review on pavement engineering research 2021

Sustainable and resilient pavement infrastructure is critical for current economic and environmental challenges. In the past 10 years, the pavement infrastructure strongly supports the rapid development of the global social economy. New theories, new methods, new technologies and new materials related to pavement engineering are emerging....

In vitro degradation and surface bioactivity of iron-matrix composites containing silicate-based bioceramic

Iron-matrix composites with calcium silicate (CS) bioceramic as the reinforcing phase were fabricated through powder metallurgy processes. The microstructures, mechanical properties, apatite deposition and biodegradation behavior of the Fe-CS composites, as well as cell attachment and proliferation on<br/>their surfaces, were characterized. In...