Zooming in on style: Exploring style perception using details of paintings

Most studies on the perception of style have used whole scenes/entire paintings; in our study, we isolated a single motif (an apple) to reduce or even eliminate the influence of composition, iconography, and other contextual information. In this article, we empirically address two fundamental questions of the existence (Experiment 1) and...

Effects of Information Architecture on the Effectiveness and User Experience of Web-Based Patient Education in Middle-Aged and Older Adults: Online Randomized Experiment

Background: Web-based patient education is increasingly offered to improve patients’ ability to learn, remember, and apply health information. Efficient organization, display, and structural design, that is, information architecture (IA), can support patients’ ability to independently use web-based patient education. However, the role of IA in...

PCADD: SNV prioritisation in Sus scrofa

Background: In animal breeding, identification of causative genetic variants is of major importance and high economical value. Usually, the number of candidate variants exceeds the number of variants that can be validated. One way of prioritizing probable candidates is by evaluating their potential to have a deleterious effect, e.g. by...

Effects of light map orientation and shape on the visual perception of canonical materials

We previously presented a systematic optics-based canonical approach to test material-lighting interactions in their full natural ecology, combining canonical material and lighting modes. Analyzing the power of the spherical harmonics components of the lighting allowed us to predict the lighting effects on material perception for generic...

Influence of Texture Structure on the Perception of Color Composition

The authors explore the influence of the structure of a texture image on the perception of its color composition through a series of psychophysical studies. They estimate the color composition of a texture by extracting its dominant colors and the associated percentages. They then synthesize new textures with the same color composition but...

Predicting variant deleteriousness in non-human species: Applying the CADD approach in mouse

Background: Predicting the deleteriousness of observed genomic variants has taken a step forward with the introduction of the Combined Annotation Dependent Depletion (CADD) approach, which trains a classifier on the wealth of available human genomic information. This raises the question whether it can be done with less data for non-human...

Asymmetric perceptual confounds between canonical lightings and materials

To better understand the interactions between material perception and light perception, we further developed our material probe MatMix 1.0 into MixIM 1.0, which allows optical mixing of canonical lighting modes. We selected three canonical lighting modes (ambient, focus, and brilliance) and created scenes to represent the three illuminations....

Sequence features of viral and human Internal Ribosome Entry Sites predictive of their activity

Translation of mRNAs through Internal Ribosome Entry Sites (IRESs) has emerged as a prominent mechanism of cellular and viral initiation. It supports cap-independent translation of select cellular genes under normal conditions, and in conditions when cap-dependent translation is inhibited. IRES structure and sequence are believed to be...

Pan-cancer subtyping in a 2D-map shows substructures that are driven by specific combinations of molecular characteristics

The use of genome-wide data in cancer research, for the identification of groups of patients with similar molecular characteristics, has become a standard approach for applications in therapy-response, prognosis-prediction, and drug-development. To progress in these applications, the trend is to move from single genome-wide measurements in a...