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McMorland, J. (author), Collu, M. (author), McMillan, D. (author), Carroll, James (author), Coraddu, A. (author)As new offshore wind development sites move further from shore and existing sites enter their post-subsidy operating period, it is expected that operational expenditure (OpEx) will increase. In order to overcome these challenges, a more flexible and cost-effective maintenance solution is needed. One such solution is opportunistic maintenance ...review 2023
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A review of operations and maintenance modelling with considerations for novel wind turbine conceptsMcMorland, Jade (author), Flannigan, Callum (author), Carroll, James (author), Collu, Maurizio (author), McMillan, David (author), Leithead, William (author), Coraddu, A. (author)New wind turbine technologies and designs are being explored in order to reduce the cost of energy from offshore wind farms. Two potential routes to a lower cost of energy are the X- Rotor Concept (XRC) and Multi-Rotor System (MRS) turbines. A key cost saving for both Novel concepts included in this paper is operation and maintenance (O&M...review 2022
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Kleikamp, H.B.C. (author), Lin, Y. (author), McMillan, D.G.G. (author), Geelhoed, Jeanine S. (author), Naus-Wiezer, Suzanne N.H. (author), Van Baarlen, Peter (author), Saha, Chinmoy (author), Louwen, Rogier (author), Sorokin, Dimitry Y. (author), van Loosdrecht, Mark C.M. (author), Pabst, Martin (author)Nonulosonic acids, commonly referred to as sialic acids, are a highly important group of nine-carbon sugars common to all domains of life. They all share biosynthetic and structural features, but otherwise display a remarkable chemical diversity. In humans, sialic acids cover all cells which makes them important for processes such as cellular...review 2020
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Marsden, S.R. (author), Mestrom, L. (author), McMillan, D.G.G. (author), Hanefeld, U. (author)The enzymatic synthesis of esters and peptides is unfavoured in aqueous solvent systems due to competing hydrolysis. This can be overcome by using energy rich substrate analogues: elimination of a good leaving group temporarily establishes more favourable equilibrium conditions, allowing for (nearly) complete conversion. While kinetically...review 2019
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Krah, Alexander (author), Zarco-Zavala, Mariel (author), McMillan, D.G.G. (author)ATP synthases catalyse the formation of ATP, the most common chemical energy storage unit found in living cells. These enzymes are driven by an electrochemical ion gradient, which allows the catalytic evolution of ATP by a binding change mechanism. Most ATP synthases are capable of catalysing ATP hydrolysis to varying degrees, and to prevent...review 2018