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Meijer, Simone (author), Karacaoglu, Merve (author), van Middendorp, Henriët (author), Veldhuijzen, Dieuwke S. (author), Jensen, Karin B. (author), Peerdeman, Kaya J. (author), Evers, A.W.M. (author)Background: Nocebo effects can adversely affect the experience of physical symptoms, such as pain and itch. Nocebo effects on itch and pain have shown to be induced by conditioning with thermal heat stimuli and reduced by counterconditioning. However, open-label counterconditioning, in which participants are informed about the placebo content...journal article 2023
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Cachera, Paul (author), Olsson, Helén (author), Coumou, Hilde (author), Jensen, Mads L. (author), Sánchez, Benjamín J. (author), Strucko, Tomas (author), van den Broek, M.A. (author), Daran, J.G. (author), Jensen, Michael K. (author), Sonnenschein, Nikolaus (author), Lisby, Michael (author), Mortensen, Uffe H. (author)Biological functions are orchestrated by intricate networks of interacting genetic elements. Predicting the interaction landscape remains a challenge for systems biology and new research tools allowing simple and rapid mapping of sequence to function are desirable. Here, we describe CRI-SPA, a method allowing the transfer of chromosomal...journal article 2023
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Sørli, Jorid B. (author), Jensen, Alexander C.Ø. (author), Mortensen, Alicja (author), Szarek, Józef (author), Gutierrez, Claudia A.T. (author), Hafez, Iosif (author), Biskos, G. (author), Hougaard, Karin S. (author), Vogel, Ulla (author)Tungsten is used in several applications and human exposure may occur. To assess its pulmonary toxicity, we exposed male mice to nose-only inhalation of tungsten particles at 9, 23 or 132 mg/m<sup>3</sup> (Low, Mid and High exposure) (45 min/day, 5 days/week for 2 weeks). Increased genotoxicity (assessed by comet assay) was seen in...journal article 2023
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Sørli, Jorid B. (author), Jensen, Alexander C.Ø. (author), Mortensen, Alicja (author), Szarek, Józef (author), Gutierrez, Claudia A.T. (author), Givelet, Lucas (author), Loeschner, Katrin (author), Loizides, Charis (author), Biskos, G. (author)Molybdenum disulphide (MoS<sub>2</sub>) is a constituent of many products. To protect humans, it is important to know at what air concentrations it becomes toxic. For this, we tested MoS<sub>2</sub> particles by nose-only inhalation in mice. Exposures were set to 13, 50 and 150 mg MoS<sub>2</sub>/m<sup>3</sup> (=8, 30 and 90 mg Mo/m<sup>3<...journal article 2023
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Karacaoglu, Merve (author), Meijer, Simone (author), Peerdeman, Kaya J. (author), Dusseldorp, Elise (author), Jensen, Karin B. (author), Veldhuijzen, Dieuwke S. (author), van Middendorp, Henriët (author), Evers, A.W.M. (author)OBJECTIVES: The current paper explores the psychological predictors of nocebo hyperalgesia and whether the reduction of nocebo hyperalgesia can be predicted by susceptibility to nocebo hyperalgesia and psychological characteristics. METHODS: Nocebo effects on pressure pain were first experimentally induced in 83 healthy female participants...journal article 2023
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Lilius, Tuomas O. (author), Mortensen, Kristian Nygaard (author), Deville, Claire (author), Lohela, Terhi J. (author), Stæger, Frederik Filip (author), Sigurdsson, Björn (author), Rosenholm, Marko (author), Beekman, F.J. (author), Jensen, Andreas I. (author)Nanoparticles are ultrafine particulate matter having considerable potential for treatment of central nervous system (CNS) disorders. Despite their tiny size, the blood-brain barrier (BBB) restricts their access to the CNS. Their direct cerebrospinal fluid (CSF) administration bypasses the BBB endothelium, but still fails to give adequate...journal article 2023
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Trabal, Guillem Gall (author), Bak, Brian Lau Verndal (author), Chen, B. Y. (author), Jensen, Simon Mosbjerg (author), Lindgaard, Esben (author)A numerical study on the feasibility of using patches of interface weakening or toughening material to trigger multiple delaminations toughening laminated composite structures against delamination is presented. The studies use an adaptive refinement formulation that uses cohesive elements to model delamination initiation and propagation. A DCB...conference paper 2022
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Trabal, Guillem Gall (author), Bak, Brian Lau Verndal (author), Chen, B. Y. (author), Jensen, Simon Mosbjerg (author), Lindgaard, Esben (author)A numerical study on toughening laminated composite materials against delamination by initiating multiple interlaminar cracks is presented. Different configurations of interface toughening and weakening patches, that modify the interface properties at selected locations, are investigated as a way to trigger multiple delaminations. Both...journal article 2022
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Boltje, D.B. (author), Hoogenboom, J.P. (author), Jakobi, A. (author), Jensen, Grant J. (author), Jonker, C.T.H. (author), Kaag, Max J. (author), de Agrela Pinto, C. (author), van der Wee, E.B. (author), Hoedt, Sander Den (author)Cryogenic electron tomography (cryo-ET) combined with sub-tomogram averaging, allows in-situ visualization and structure determination of macromolecular complexes at sub-nanometre resolution. Cryogenic focused ion beam (cryo-FIB) micromachining is used to prepare a thin lamella-shaped sample out of a frozen-hydrated cell for cryo-ET imaging,...journal article 2022
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Schneider, F. (author), Jensen, Anders Fjendbo (author), Daamen, W. (author), Hoogendoorn, S.P. (author)In this paper, we study observed cycling distances within an accessibility framework, using data from the Netherlands, the Copenhagen Metropolitan Area and the Freiburg Region. As a scope, we look at outbound trips in home-based tours which include a single destination. We relate these observed cycling distances to a rich set of explanatory...journal article 2022
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van Putten, R. (author), Eyke, Natalie S. (author), Baumgartner, L.M. (author), Schultz, Victor L. (author), Filonenko, G.A. (author), Jensen, Klavs F. (author), Pidko, E.A. (author)Automation and microfluidic tools potentially enable efficient, fast, and focused reaction development of complex chemistries, while minimizing resource- and material consumption. The introduction of automation-assisted workflows will contribute to the more sustainable development and scale-up of new and improved catalytic technologies....journal article 2022
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- Evers, A.W.M. (author), Colloca, Luana (author), Blease, Charlotte (author), Gaab, Jens (author), Jensen, Karin B. (author), Atlas, Lauren Y. (author), Beedie, Chris J. (author), Benedetti, Fabrizio (author), Bingel, Ulrike (author) journal article 2021
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van der Voordt, Theo (author), Jensen, Per Anker (author)This chapter presents a theory about the added value of buildings, workplaces, facilities and services. Traditionally, value is mainly associated with financial parameters. This chapter presents a more holistic approach. It explains the meaning of value and discusses different value types and value parameters. It shows that prioritized values...book chapter 2021
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van der Voordt, Theo (author), Jensen, Per Anker (author)Purpose: This paper aims to explore the added value of healthy workplaces for employees and organizations, in particular regarding employee satisfaction, labour productivity and facility cost. Design/methodology/approach: The paper is based on a narrative review of journal papers and other sources covering the fields of building research,...review 2021
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Hallin, E.C. (author), Hofstede, Jacobus L.A. (author), Martinez, Grit (author), Jensen, Jürgen (author), Baron, Nina (author), Heimann, Thorsten (author), Kroon, Aart (author), Arns, Arne (author), Almström, Björn (author)From November 12th to 13th in 1872, an extreme coastal flood event occurred in the south Baltic Sea. An unusual combination of winds created a storm surge reaching up to 3.5 m above mean sea level, which is more than a meter higher than all other observations over the past 200 years. On the Danish, German, and Swedish coasts, about 300 people...journal article 2021
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Vogel, S. (author), Thi Nguyen, Ha (author), Stevic, M. (author), Jensen, Tue Vissing (author), Heussen, Kai (author), Subramaniam Rajkumar, Vetrivel (author), Monti, Antonello (author)This paper presents an approach to extend the capabilities of smart grid laboratories through the concept of Power Hardware-in-The-Loop (PHiL) testing by re-purposing existing grid-forming converters. A simple and cost-effective power interface, paired with a remotely located Digital Real-Time Simulator (DRTS), facilitates Geographically...journal article 2020
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Holtz, Georg (author), Schnülle, Christian (author), Yadack, Malcolm (author), Friege, J.M. (author), Jensen, T. (author), Thier, Pablo (author), Viebahn, Peter (author), Chappin, E.J.L. (author)The German Energiewende is a deliberate transformation of an established industrial economy towards a nearly CO2-free energy system accompanied by a phase out of nuclear energy. Its governance requires knowledge on how to steer the transition from the existing status quo to the target situation (transformation knowledge). The energy system is,...journal article 2020
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Jensen, Per Anker (author), van der Voordt, Theo (author)Purpose: The purpose of this paper is to present an empirical-based typology of facilities management (FM) and corporate real estate management (CREM) interventions that can add value to the core business of organisations and possibly the wider society. The typology is explained, elaborated and discussed with the aim to reach a deeper...journal article 2020
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Dignum, Frank (author), Dignum, Virginia (author), Davidsson, Paul (author), Ghorbani, Amineh (author), van der Hurk, Mijke (author), Jensen, Maarten (author), Kammler, Christian (author), Lorig, Fabian (author), Ludescher, Luis Gustavo (author), Melchior, Alexander (author), Mellema, René (author), Pastrav, Cezara (author), Vanhee, Loïs (author), Verhagen, Harko (author)During the COVID-19 crisis there have been many difficult decisions governments and other decision makers had to make. E.g. do we go for a total lock down or keep schools open? How many people and which people should be tested? Although there are many good models from e.g. epidemiologists on the spread of the virus under certain conditions,...journal article 2020
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Cash, Philip (author), Khadilkar, Pramod (author), Jensen, Joanna (author), Dusterdich, Camilla (author), Mugge, R. (author)Behavioural design has emerged as a critical new area of research and practice. However, despite the development of extensive lists of possible problem features and suggested solution principles there is little guidance on how these should be connected. Therefore, in this work we systematically examine interactions between major problem features...journal article 2020