Haridas, M. (author), Bisterfeld, C. (author), Chen, Le Min (author), Marsden, S.R. (author), Tonin, F. (author), Medici, R. (author), Iribarren, Adolfo (author), Lewkowicz, Elizabeth (author), Hagedoorn, P.L. (author), Hanefeld, U. (author), Abdelraheem, E.M.M. (author) DERA (2-Deoxy-D-ribose 5-phosphate aldolase) is the only known aldolase that accepts two aldehyde substrates, which makes it an attractive catalyst for the synthesis of a chiral polyol motif that is present in several pharmaceuticals, such as atorvastatin and pravastatin. However, inactivation of the enzyme in the presence of aldehydes...
journal article 2020
