Enhancing trigger sensitivity of nanocarriers through organocatalytic oxidant activation

The redox balance in tumor and diseased cells often leads to the production of reactive oxygen species (ROS). Many ROS-responsive materials based on sulfur oxidation have been reported with the goal of achieving controlled delivery at the tumor. However, these materials often lack responsiveness to low ROS concentrations present in the tumor...

Biomimetic Strain-Stiffening Self-Assembled Hydrogels

Supramolecular structures with strain-stiffening properties are ubiquitous in nature but remain rare in the lab. Herein, we report on strain-stiffening supramolecular hydrogels that are entirely produced through the self-assembly of synthetic molecular gelators. The involved gelators self-assemble into semi-flexible fibers, which thereby...