ZIMFLUX: Single molecule localization microscopy with patterned illumination in 3D

Three dimensional modulation-enhanced single-molecule localization techniques, such as ModLoc, offer advancements in axial localization precision across the entire field of view and axial capture range, by applying phase shifting to the illumination pattern. However, this improvement is limited by the pitch of the illumination pattern that...

Quantum Technologies and Society: Towards a Different Spin

Due primarily to technological advances over the last decade, quantum research has become a key priority area for science and technology policy all over the world. With this manifesto, we wish to prevent quantum technology from running into fiascos of implementation at the interface of science and society. To this end, we identify key stumbling...

Photon count estimation in single-molecule localization microscopy

Recently, Franke, Sauer and van de Linde introduced a way to estimate the axial position of single-molecules (TRABI). To this end, they compared the detected photon count from a temporal radial-aperture-based intensity estimation to the estimated count from Gaussian point-spread function (PSF) fitting to the data. Empirically they found this...

Local control of cognitive radio networks

In a network deployment, a cognitive radio will have to perform two fundamental tasks. First, each cognitive radio needs to optimize its internal operation, and second, it needs to derive a configuration that will enable and optimize communication with other nodes in the network. This latter requirement, however, relies on knowledge about the...