A multi-axis robot-based bioprinting system supporting natural cell function preservation and cardiac tissue fabrication

Despite the recent advances in artificial tissue and organ engineering, how to generate large size viable and functional complex organs still remains as a grand challenge for regenerative medicine. Three-dimensional bioprinting has demonstrated its advantages as one of the major methods in fabricating simple tissues, yet it still faces...

An omics-based framework for assessing the health risk of antimicrobial resistance genes

Antibiotic resistance genes (ARGs) are widespread among bacteria. However, not all ARGs pose serious threats to public health, highlighting the importance of identifying those that are high-risk. Here, we developed an ‘omics-based’ framework to evaluate ARG risk considering human-associated-enrichment, gene mobility, and host pathogenicity....

Tidal-flat reclamation aggravates potential risk from storm impacts

A better understanding of how tidal-flat reclamation changes the flood hazard is critical for climate-proofing coastal flood defense design of heavily urbanized areas. Since the 1950s, large-scale reclamation has been performed along the Shanghai coast, China, to fulfill the land demands of city expansion. We now show that the loss of tidal...

Deep characteristics analysis on travel time of emergency traffic

Owing to the rapid development of emergency rescue transportation in cities and the frequent emergencies, demand for emergency rescue is increasing drastically. How to select an emergency rescue route quickly and shorten the rescue travel time under the condition of limited urban road resources is of great significance. Based on the...

Analysis on the Water Exchange between the Main Stream of the Yangtze River and the Poyang Lake

Analysis on the hydrologic characteristics of the main stream of the Yangtze River and Poyang Lake were studied to discuss the water exchange between the main stream of the Yangtze River and Poyang Lake before and after the operation of Three Gorges Reservoir, as well as in the typical dry year of 2006. The annual runoff distribution for dry...