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Rodriguez Hernandez, K.E. (author), de Groot, J.H. (author), Baas, Frank (author), Stijntjes, M. (author), Grootendorst, E.R.M. (author), Schiemanck, S.K. (author), van der Helm, F.C.T. (author), van der Kooij, H. (author), Mugge, W. (author)Individuals with an upper motor neuron syndrome, e.g., stroke survivors, may have a pathological increase of passive ankle stiffness due to spasticity, that impairs ankle function and activities such as walking. To improve mobility, walking aids such as ankle-foot orthoses and orthopaedic shoes are prescribed. However, these walking aids...journal article 2023
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Roelofs, Jolanda M.B. (author), Zandvliet, Sarah B. (author), Schut, I.M. (author), Huisinga, Anouk C.M. (author), Schouten, A.C. (author), Hendricks, Henk T. (author), de Kam, Digna (author), Aerden, Leo A.M. (author), Bussmann, J.B.J. (author), Geurts, Alexander C.H. (author), Weerdesteyn, Vivian (author)Background: After mild stroke persistent balance limitations may occur, creating a risk factor for fear of falling, falls, and reduced activity levels. Objective. To investigate whether individuals in the chronic phase after mild stroke show balance and gait limitations, elevated fall risk, reduced balance confidence, and physical activity...journal article 2023
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Ellis, Michael D. (author), Gurari, Netta (author), Gerritsen, Ninette T.A. (author), Lee, Sabrina M. (author), Wang, Amy (author), Dewald, J.P.A. (author)Muscle tissue is prone to changes in composition and architecture following stroke. Changes in muscle tissue of the extremities are thought to increase resistance to muscle elongation or joint torque under passive conditions. These effects likely compound neuromuscular impairments, exacerbating movement function. Unfortunately, conventional...journal article 2023
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Lemke, M. (author), Rodríguez Ramírez, Edgar (author), Robinson, Brian (author)Stroke causes damage to the brain, often resulting in weakness or paralysis on one side of the body. Everyday objects such as smartphones can play an im-portant role after a stroke facilitating participation in daily activities. However, commercial smartphones can be challenging to use, and people with stroke of-ten adjust their behavior to...conference paper 2022
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van Kordelaar, J. (author), van de Ruit, M.L. (author), Solis Escalante, T. (author), Aerden, Leo A.M. (author), Meskers, Carel G.M. (author), van Wegen, Erwin E.H. (author), Schouten, A.C. (author), Kwakkel, Gert (author), van der Helm, F.C.T. (author)Background: Proprioception is important for regaining motor function in the paretic upper extremity after stroke. However, clinical assessments of proprioception are subjective and require verbal responses from the patient to applied proprioceptive stimuli. Cortical responses evoked by robotic wrist perturbations and measured by...journal article 2021
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van der Krogt, Hanneke (author), Kouwijzer, Ingrid (author), Klomp, A. (author), Meskers, Carel G.M. (author), Arendzen, J. Hans (author), de Groot, Jurriaan H. (author)Purpose: Loss of selective muscle activation after stroke contributes to impaired arm function, is difficult to quantify and is not systematically assessed yet. The aim of this study was to describe and validate a technique for quantification of selective muscle activation of wrist flexor and extensor muscles in a cohort of post-stroke...journal article 2020
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Filatova, O.G. (author)Human brain consists of grey and white matter. Grey matter largely forms the<br/>outer layer of the brain, and is responsible for decision making and functioning<br/>of the human body. Complementary, the white matter (WM) contains the<br/>communication pathways between the grey matter areas. Diffusion-weighted<br/>magnetic resonance imaging ...doctoral thesis 2019
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de Gooijer-van de Groep, Karin L. (author), de Groot, Jurriaan H. (author), van der Krogt, Hanneke (author), de Vlugt, E. (author), Arendzen, J. Hans (author), Meskers, Carel G.M. (author)Background. The mechanism and time course of increased wrist joint stiffness poststroke and clinically observed wrist flexion deformity is still not well understood. The components contributing to increased joint stiffness are of neural reflexive and peripheral tissue origin and quantified by reflexive torque and muscle slack length and...journal article 2018
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Evans, Tavia E. (author), O'Sullivan, Michael J. (author), De Groot, Marius (author), Niessen, W.J. (author), Hofman, Albert (author), Krestin, Gabriel P. (author), Van Der Lugt, Aad (author), Portegies, Marileen L P (author), Koudstaal, Peter J. (author), Bos, Daniel (author), Vernooij, Meike W. (author), Ikram, M. Arfan (author)Background and Purpose - The presence of subclinical vascular brain disease, including white matter lesions and lacunar infarcts, substantially increases the risk of clinical stroke. White matter microstructural integrity is considered an earlier, potentially better, marker of the total burden of vascular brain disease. Its association with...journal article 2016
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Ikram, M.A. (author), Van der Lugt, A. (author), Niessen, W.J. (author), Koudstaal, P.J. (author), Krestin, G.P. (author), Hofman, A. (author), Bos, D. (author), Vernooij, M.W. (author)Imaging plays an essential role in research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to elucidate the causes of neurological disease by performing imaging of the brain in a prospective population-based setting. Initially, in 1995 and 1999, random...journal article 2015
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Meskers, C.G.M. (author), De Groot, J. (author), De Vlugt, E. (author), Schouten, A.C. (author)Progress in diagnosis and treatment of movement disorders after neurological diseases like stroke, cerebral palsy (CP), dystonia and at old age requires understanding of the altered capacity to adequately respond to physical obstacles in the environment. With posture and movement disorders, the control of muscles is hampered, resulting in...journal article 2015
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Van der Krogt, H. (author), Klomp, A. (author), De Groot, J.H. (author), De Vlugt, E. (author), Van der Helm, F.C.T. (author), Meskers, C.G.M. (author), Arendzen, J.H. (author)Background: Understanding movement disorder after stroke and providing targeted treatment for post stroke patients requires valid and reliable identification of biomechanical (passive) and neural (active and reflexive) contributors. Aim of this study was to assess test-retest reliability of passive, active and reflexive parameters and to...journal article 2015
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Atherosclerotic plaque fibrous cap assessment under an oblique scan plane orientation in carotid MRINieuwstadt, H.A. (author), Van der Lugt, A. (author), Kassar, Z.A.M. (author), Breeuwer, M. (author), Van der Steen, A.F.W. (author), Gijsen, F.J.H. (author)Carotid magnetic resonance imaging (MRI) is used to noninvasively assess atherosclerotic plaque fibrous cap (FC) status, which is closely related to ischemic stroke. Acquiring anisotropic voxels improves in-plane visualization, however, an oblique scan plane orientation could then obscure a FC (i.e., contrast below the noise level) and thus...journal article 2014
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Westerveld, A.J. (author), Schouten, A.C. (author), Veltink, P.H. (author), Van der Kooij, H. (author)Background Stroke survivors often have difficulties in manipulating objects with their affected hand. Thumb control plays an important role in object manipulation. Surface functional electrical stimulation (FES) can assist movement. We aim to control the 2D thumb force by predicting the sum of individual muscle forces, described by a sigmoidal...journal article 2013
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Koopman, B. (author), Van Asseldonk, E.H.F. (author), Van der Kooij, H. (author)Background Robot-aided gait training is an emerging clinical tool for gait rehabilitation of neurological patients. This paper deals with a novel method of offering gait assistance, using an impedance controlled exoskeleton (LOPES). The provided assistance is based on a recent finding that, in the control of walking, different modules can be...journal article 2013
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Van der Krogt, H.J.M. (author), Meskers, C.G.M. (author), De Groot, J.H. (author), Klomp, A. (author), Arendzen, J.H. (author)Background: Movement disorders after stroke are still captured by clinical gaze and translated to ordinal scores of low resolution. There is a clear need for objective quantification, with outcome measures related to pathophysiological background. Neural and non-neural contributors to joint behavior should be separated using different...journal article 2012
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Bregman, D.J.J. (author), Van der Krogt, M.M. (author), De Groot, V. (author), Harlaar, J. (author), Wisse, M. (author), Collins, S.H. (author)Background In stroke and multiple sclerosis patients, gait is frequently hampered by a reduced ability to push-off with the ankle caused by weakness of the plantar-flexor muscles. To enhance ankle push-off and to decrease the high energy cost of walking, spring-like carbon-composite Ankle Foot Orthoses are frequently prescribed. However, it is...journal article 2011
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Ikram, M.A. (author), Van der Lugt, A. (author), Niessen, W.J. (author), Krestin, G.P. (author), Koudstaal, P.J. (author), Hofman, A. (author), Breteler, M.M.B. (author), Vernooij, M.W. (author)Neuroimaging plays an important role in etiologic research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to unravel causes of neurological disease by performing neuroimaging in a population-based longitudinal setting. In 1995 and 1999 random subsets of the...journal article 2011
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Campfens, S.F. (author), Zandvliet, S.B. (author), Meskers, C.G.M. (author), Schouten, A.C. (author), Van Putten, M.J.A.M. (author), Van der Kooij, H. (author)Abstract The possibility to regain motor function after stroke depends on the intactness of motor and sensory pathways. In this study, we evaluated afferent sensory pathway information transfer and processing after stroke with the coherence between cortical activity and a position perturbation (position-cortical coherence, PCC). Eleven subacute...journal article