Asymmetric α-benzylation of cyclic ketones enabled by concurrent chemical aldol condensation and biocatalytic reduction

Chemoenzymatic cascade catalysis has emerged as a revolutionary tool for streamlining traditional retrosynthetic disconnections, creating new possibilities for the asymmetric synthesis of valuable chiral compounds. Here we construct a one-pot concurrent chemoenzymatic cascade by integrating organobismuth-catalyzed aldol condensation with ene...

A novel GA-LSTM-based prediction method of ship energy usage based on the characteristics analysis of operational data

Optimization of ship energy efficiency is an efficient measure to decrease fuel usage and emissions in the shipping industry. The accurate prediction model of ship energy usage is the basis to achieve optimization of ship energy efficiency. This study investigates the sequential properties of the actual voyage data from a VLOC. On this basis,...