- document
-
Millán, Ana P. (author), van Straaten, Elisabeth C. W. (author), Stam, Cornelis J. (author), Nissen, Ida A. (author), Idema, Sander (author), Baayen, Johannes C. (author), Van Mieghem, P.F.A. (author), Hillebrand, Arjan (author)Epilepsy surgery is the treatment of choice for drug-resistant epilepsy patients, but only leads to seizure freedom for roughly two in three patients. To address this problem, we designed a patient-specific epilepsy surgery model combining large-scale magnetoencephalography (MEG) brain networks with an epidemic spreading model. This simple...journal article 2023
- document
-
Millán, Ana P. (author), van Straaten, Elisabeth C.W. (author), Stam, Cornelis J. (author), Nissen, Ida A. (author), Idema, Sander (author), Baayen, Johannes C. (author), Van Mieghem, P.F.A. (author), Hillebrand, Arjan (author)Epilepsy surgery is the treatment of choice for drug-resistant epilepsy patients. However, seizure-freedom is currently achieved in only 2/3 of the patients after surgery. In this study we have developed an individualized computational model based on MEG brain networks to explore seizure propagation and the efficacy of different virtual...journal article 2022
- document
-
Nissen, Ida A. (author), Millán, Ana P. (author), Stam, Cornelis J. (author), van Straaten, Elisabeth C.W. (author), Douw, Linda (author), Pouwels, Petra J.W. (author), Idema, Sander (author), Baayen, Johannes C. (author), Velis, Demetrios (author), Van Mieghem, P.F.A. (author), Hillebrand, Arjan (author)The success of epilepsy surgery in patients with refractory epilepsy depends upon correct identification of the epileptogenic zone (EZ) and an optimal choice of the resection area. In this study we developed individualized computational models based upon structural brain networks to explore the impact of different virtual resections on the...journal article 2021