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Taskesen, E. (author), Huisman, S.M.H. (author), Mahfouz, A.M.E.T.A. (author), Krijthe, J.H. (author), de Ridder, J. (author), van de Stolpe, A. (author), van den Akker, E.B. (author), Verhaegh, Wim (author), Reinders, M.J.T. (author)
The use of genome-wide data in cancer research, for the identification of groups of patients with similar molecular characteristics, has become a standard approach for applications in therapy-response, prognosis-prediction, and drug-development. To progress in these applications, the trend is to move from single genome-wide measurements in a...
journal article 2016
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Michaut, M (author), Chin, SF (author), Majewski, I (author), Severson, TM (author), Bismeijer, T (author), de Koning, L (author), Peeters, JK (author), Schouten, PC (author), Rueda, OM (author), Bosma, AJ (author), Wessels, L.F.A. (author)
Invasive lobular carcinoma (ILC) is the second most frequently occurring histological breast cancer subtype after invasive ductal carcinoma (IDC), accounting for around 10% of all breast cancers. The molecular processes that drive the development of ILC are still largely unknown. We have performed a comprehensive genomic, transcriptomic and...
journal article 2016