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Multi-scale in silico and ex silico mechanics of 3D printed cochlear implants for local drug delivery

Isaakidou, A. (author), Ganjian, M. (author), van Hoften, R. (author), Cruz Saldivar, M. (author), Leeflang, M.A. (author), Groetsch, A. (author), Wątroba, M. (author), Schwiedrzik, J. (author), Mirzaali, Mohammad J. (author), Apachitei, I. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)

The currently available treatments for inner ear disorders often involve systemic drug administration, leading to suboptimal drug concentrations and side effects. Cochlear implants offer a potential solution by providing localized and sustained drug delivery to the cochlea. While the mechanical characterization of both the implants and their...

journal article 2024

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Optical Methods for Brain Tumor Detection: A Systematic Review

Burström, Gustav (author), Amini, Misha (author), El-Hajj, Victor Gabriel (author), Arfan, Arooj (author), Gharios, Maria (author), Buwaider, Ali (author), Losch, M.S. (author), Manni, Francesca (author), Edström, Erik (author), Terander, Adrian Elmi (author)

Background: In brain tumor surgery, maximal tumor resection is typically desired. This is complicated by infiltrative tumor cells which cannot be visually distinguished from healthy brain tissue. Optical methods are an emerging field that can potentially revolutionize brain tumor surgery through intraoperative differentiation between healthy...

review 2024

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Towards labonachip optical trapping and Raman spectroscopy of extracellular vesicles using multiwaveguide traps

Loozen, G.B. (author)

Optofluidic lab-on-a-chips (LOCs) employing a dual-waveguide trap for optical trapping and Raman spectroscopy have proven to be attractive and potent tools for high throughput chemical fingerprinting of bio-particles for disease diagnosis. Among the relevant bio-particles are extracellular vesicles (EVs) which a been proven through recent...

doctoral thesis 2023

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In Situ Characterization of the Reaction-Diffusion Behavior during the Gradient Interphase Formation of Polyetherimide with a High-Temperature Epoxy System

Zweifel, Lucian (author), Brauner, Christian (author), Teuwen, Julie J.E. (author), Dransfeld, C.A. (author)

This study presents two novel methods for in situ characterization of the reaction-diffusion process during the co-curing of a polyetherimide thermoplastic interlayer with an epoxy-amine thermoset. The first method was based on hot stage experiments using a computer vision point tracker algorithm to detect and trace diffusion fronts, and the...

journal article 2022

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Spectroscopic review of hydrogenated, carbonated and oxygenated group IV alloys

de Vrijer, T. (author), Bouazzata, Bilal (author), Smets, A.H.M. (author)

Semiconductors based on group IV elements are widely used in the fields of micro-electronics, optics and photonics. The group IV alloys are processed using plasma enhanced chemical vapor deposition and its opto-electrical properties are a result of the material composition and structure. Infrared and Raman spectroscopy are complementary and...

journal article 2022

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The interaction of light with WS2 nanostructures

Komen, I. (author)

In this thesis we describe three results of the interaction between WS2 and light: photoluminescence, the formation of exciton-polaritons and Raman scattering. The chirality of the photoluminescence interaction between WS2 and light opens the way for applictions in nanophotonics and specifically valleytronics, the field of interacting with and...

doctoral thesis 2021

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Optimized graphene electrodes for contacting graphene nanoribbons

Braun, Oliver (author), Overbeck, Jan (author), El Abbassi, M. (author), Käser, Silvan (author), Furrer, Roman (author), Olziersky, Antonis (author), Flasby, Alexander (author), Borin Barin, Gabriela (author), Perrin, M.L. (author)

Atomically precise graphene nanoribbons (GNRs) are a promising emerging class of designer quantum materials with electronic properties that are tunable by chemical design. However, many challenges remain in the device integration of these materials, especially regarding contacting strategies. We report on the device integration of uniaxially...

journal article 2021

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Origin of Relaxor Behavior in Barium-Titanate-Based Lead-Free Perovskites

Veerapandiyan, Vignaswaran (author), Popov, Maxim N. (author), Mayer, Florian (author), Spitaler, Jürgen (author), Svirskas, Sarunas (author), Kalendra, Vidmantas (author), Lins, Jonas (author), Canu, Giovanna (author), Braga Groszewicz, P. (author)

It is well known that disordered relaxor ferroelectrics exhibit local polar correlations. The origin of localized fields that disrupt long-range polar order for different substitution types, however, is unclear. Currently, it is known that substituents of the same valence as Ti⁴⁺ at the B-site of barium titanate lattice produce...

journal article 2021

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Experimental study on needle insertion force to minimize tissue deformation in tongue tissue

Aaboubout, Y. (author), Nunes Soares, M. R. (author), Barroso, E. M. (author), van der Sar, L. C. (author), Bocharnikov, A. (author), Usenov, I. (author), Artyushenko, V. (author), Caspers, P. J. (author), Koljenović, S. (author), Bakker Schut, T. C. (author), van den Dobbelsteen, J.J. (author), Puppels, G. J. (author)

This study reports on the effects of insertion velocity, needle tip geometry and needle diameter on tissue deformation and maximum insertion force. Moreover, the effect of multiple insertions with the same needle on the maximum insertion force is reported. The tissue deformation and maximum insertion force strongly depend on the insertion...

journal article 2021

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Controlled Quantum Dot Formation in Atomically Engineered Graphene Nanoribbon Field-Effect Transistors

El Abbassi, M. (author), Perrin, M.L. (author), Barin, Gabriela Borin (author), Sangtarash, Sara (author), Overbeck, Jan (author), Braun, Oliver (author), Lambert, Colin J. (author), Sun, Qiang (author), Prechtl, Thorsten (author)

Graphene nanoribbons (GNRs) have attracted strong interest from researchers worldwide, as they constitute an emerging class of quantum-designed materials. The major challenges toward their exploitation in electronic applications include reliable contacting, complicated by their small size (<50 nm), and the preservation of their physical...

journal article 2020

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Tunable Photodetectors via In Situ Thermal Conversion of TiS₃ to TiO₂

Ghasemi, Foad (author), Frisenda, Riccardo (author), Flores, Eduardo (author), Papadopoulos, N. (author), Biele, Robert (author), de Lara, David Perez (author), van der Zant, H.S.J. (author), Watanabe, Kenji (author), Castellanos-Gomez, Andres (author)

In two-dimensional materials research, oxidation is usually considered as a common source for the degradation of electronic and optoelectronic devices or even device failure. However, in some cases a controlled oxidation can open the possibility to widely tune the band structure of 2D materials. In particular, we demonstrate the controlled...

journal article 2020

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Robust Sample Preparation of Large-Area In- and Out-of-Plane Cross Sections of Layered Materials with Ultramicrotomy

Cichocka, M.O. (author), Bolhuis, M. (author), van Heijst, S.E. (author), Conesa Boj, S. (author)

Layered materials (LMs) such as graphene or MoS2 have attracted a great deal of interest recently. These materials offer unique functionalities due to their structural anisotropy characterized by weak van der Waals bonds along the out-of-plane axis and covalent bonds in the in-plane direction. A central requirement to access the structural...

journal article 2020

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Graphene Isotope Superlattices with Strongly Diminished Thermal Conductivity for Thermoelectric Applications

Whiteway, Eric (author), Lee, M. (author), Hilke, Michael (author)

Graphene has a high intrinsic thermal conductivity and a high electron mobility. The thermal conductivity of graphene can be significantly reduced when different carbon isotopes are mixed, which can enhance the performance of thermoelectric devices. Here we synthesize isotopic 12C/13C random mixes and isotope superlattices (SLs) with periods...

journal article 2020

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Raman Fingerprint of Pressure-Induced Phase Transitions in TiS₃Nanoribbons: Implications for Thermal Measurements under Extreme Stress Conditions

Mishra, K. K. (author), Ravindran, T. R. (author), Island, J.O. (author), Flores, Eduardo (author), Ares, Jose Ramon (author), Sanchez, Carlos (author), Ferrer, Isabel J. (author), van der Zant, H.S.J. (author), Castellanos-Gomez, Andres (author)

Two-dimensional layered trichalcogenide materials have recently attracted the attention of the scientific community because of their robust mechanical and thermal properties and applications in opto- and nanoelectronics devices. We report the pressure dependence of out-of-plane Ag Raman modes in high quality few-layer titanium trisulfide ...

journal article 2020

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Integrated photonics multi-waveguide devices for optical trapping and Raman spectroscopy: design, fabrication and performance demonstration

Loozen, G.B. (author), Karuna, A. (author), Rafiee Fanood, M.M. (author), Schreuder, Erik (author), Caro-Schuurman, J. (author)

We realized integrated photonics multi-waveguide devices for optical trapping and Raman spectroscopy of particles in a fluid. In these devices, multiple beams directed towards the device center lead to a local field enhancement around this center and thus counteract the effect of light concentration near the facets, which is a disadvantage of...

journal article 2020

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Raman based identification of on-chip trapped single micro-organisms: A feasibility study

Heldens, J.T. (author)

An important aspect in increasing our health and safety is the development of new sensors for screening drinking water samples for the presence of microbiological contaminants.The main problem associated with the detection and identification of these microbial contaminants is the long process time. The majority of the time is required fortheir...

doctoral thesis 2019

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Transfer-free graphene-based differential pressure sensor

Ramesha, Raghutham (author), Vollebregt, S. (author), Sarro, Pasqualina M (author)

Graphene is an attractive material to be used for pressure sensors due to its thinness, electrical conductivity, and potential high gauge factor. One of the issues with processing graphene is the scalability, which is largely limited by the transfer process that is required for graphene deposited by chemical vapour deposition (CVD). In this...

conference paper 2019

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Lateral adsorbate interactions inhibit HCOO⁻ while promoting CO selectivity for CO₂ electrocatalysis on silver

Bohra, D. (author), Ledezma Yanez, I.D. (author), Li, G. (author), de Jong, W. (author), Pidko, E.A. (author), Smith, W.A. (author)

Ag is a promising catalyst for the production of carbon monoxide (CO) via the electrochemical reduction of carbon dioxide (CO₂ER). Herein, we study the role of the formate (HCOO⁻) intermediate *OCHO, aiming to resolve the discrepancy between the theoretical understanding and experimental performance of Ag. We show that...

journal article 2019

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Structural and thermodynamic study of Cs₃Na(MoO₄)₂: Margin to the safe operation of sodium cooled fast reactors

Smith, A.L. (author), Kauric, G.P.T.F. (author), van Eijck, L. (author), Goubitz, K. (author), Clavier, N. (author), Wallez, G. (author), Konings, R. (author)

Neutron diffraction measurements of the double molybdate Cs₃Na(MoO₄)₂ have been performed for the first time in this work and the crystal structure refined using the Rietveld method. The thermal expansion of this trigonal phase, in space group P3¯m1, measured using high temperature X-ray diffraction (XRD),...

journal article 2019

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Highly anisotropic mechanical and optical properties of 2D layered As₂S₃ membranes

Siskins, M. (author), Lee, M. (author), Alijani, F. (author), Van Blankenstein, Mark R. (author), Davidovikj, D. (author), van der Zant, H.S.J. (author), Steeneken, P.G. (author)

Two-dimensional (2D) materials with strong in-plane anisotropy are of interest for enabling orientation-dependent, frequency-tunable, optomechanical devices. However, black phosphorus (bP), the 2D material with the largest anisotropy to date, is unstable as it degrades in air. In this work we show that As₂S₃ is an...

journal article 2019