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Heijnen, J.J. (author), Van Loosdrecht, M.C.M. (author)The invention relates to a method of acquiring granular growth of a microorganism in a reactor containing a liquid medium. Surprisingly, according to the invention, aerobic microorganisms also can be induced to granular growth by maintaining specific culture conditions. During a first step an oxygen-containing gas is supplied and the reactor...patent 1998
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Litjens, M.J.J. (author), Straathof, A.J.J. (author), Jongejan, J.A. (author), Heijnen, J.J. (author)The invention relates to a method of preparing a reaction product such as a primary amide, by means of two reagents A and B, which reagents form a salt that impedes fast conversion. The concentrations of the reagent A and the reagent B are chosen such that they comply with formula (I) wherein [A]T represents the concentration of the first...patent 2000
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Baart, G.J.E. (author), Beauprez, J.J.R. (author), Foulquie, M.M.R. (author), Heijnen, J.J. (author), Maertens, J. (author)The present invention relates to a method for obtaining enhanced metabolite production in micro-organisms, and to mutants and/or transformants obtained with said method. More particularly, it relates to bacterial mutants and/or transformants for enhanced succinate production, especially mutants and/or transformants that are affected in the...patent 2010
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Van der Wielen, L.A.M. (author), Heijnen, J.J. (author)The present invention is directed to a process for the continuous biological production of lipids, hydrocarbons, hydrocarbon like material or mixtures thereof by conversion of a suitable substrate using micro-organisms, in which process the said substrate is continuously, anaerobically fermented to produce lipids, hydrocarbons, hydrocarbon like...patent 2010