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Zonneveld, Hazel I. (author), Pruim, R.H.R. (author), Bos, Daniel (author), Vrooman, Henri A. (author), Muetzel, Ryan L. (author), Hofman, Albert (author), Rombouts, Serge ARB (author), Niessen, W.J. (author), More Authors (author)
Structural brain markers are studied extensively in the field of neurodegeneration, but are thought to occur rather late in the process. Functional measures such as functional connectivity are gaining interest as potentially more subtle markers of neurodegeneration. However, brain structure and function are also affected by ‘normal’ brain...
journal article 2019
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Bos, R.K. (author), Nizamis, Kostas (author), Plettenburg, D.H. (author), Herder, J.L. (author)
People with Duchenne muscular dystrophy are currently in need of assistive robotics to improve their hand function and have a better quality of life. However, none of the available active hand orthoses is able to address to their specific needs. In this study, the use of hydraulic technology is proposed in the design of an active hand...
conference paper 2018
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Borg Costanzi, C. (author), Ahmed, Z. Y. (author), Schipper, H.R. (author), Bos, F. (author), Knaack, U. (author)
One of the geometrical restrictions associated with printed paste materials such as concrete, is that material must be self-supporting during printing. In this research paper a new methodology for 3D Printing Concrete onto a temporary freeform surface is presented. This is achieved by setting up a workflow for combining a Flexible Mould...
journal article 2018
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Khalilnezhad, H. (author), Popov, M. (author), van der Sluis, L. (author), Bos, Jorrit A. (author), de Jong, Jan P.W. (author), Ametani, A. (author)
Zero-missing is a phenomenon in shunt compensated cable systems in which the current through the line breaker does not cross the zero point for several cycles. This paper deals with a thorough investigation on countermeasures of the zero-missing phenomenon in transmission systems and determines the requirements, benefits, and risks of...
journal article 2018
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Bos, R. (author)
Wind turbines are the largest rotating machines on the planet, operating in some of the most remote and hostile areas. During a lifespan of several decades, they have to withstand storms, waves, and gusts (and preferably produce electricity in the process). Yet, designers cannot make them too strong. Every additional kilogram of mass has to be...
doctoral thesis 2017
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Bos, Martijn (author)
Non-Newtonian foam flow in a reservoir can be modeled numerically by discretization of the corresponding analytical formulas. The injection of foam is compared to the injection of water by comparing the injection pressures, which is represented as a dimensionless pressure rise at the injection well. The model first applies the forward-difference...
bachelor thesis 2017
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Bos, Boy Gustaaf Cornelis (author), Thoen, D.J. (author), Haalebos, E.A.F. (author), Gimbel, P. M.L. (author), Klapwijk, T.M. (author), Baselmans, J.J.A. (author), Endo, A. (author)
The superconducting critical temperature (T-\mathrm{c} > 15 K) of niobium titanium nitride (NbTiN) thin films allows for low-loss circuits up to 1.1 THz, enabling on-chip spectroscopy and multipixel imaging with advanced detectors. The drive for large-scale detector microchips is demanding NbTiN films with uniform properties over an...
journal article 2017
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Bos, S. (author)
This thesis describes how multimodal sensor data from a 3D sensor and microphone array can be processed with deep neural networks such that its fusion, the trained neural network, is a) more robust to noise, b) outperforms unimodal recognition and c) enhances unimodal recognition in absence of multimodal data. We built a framework for a complete...
master thesis 2017
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Schipper, H.R. (author), Borg Costanzi, C. (author), Bos, Freek (author), Ahmed, Z (author), Wolfs, R. (author)
It is no secret that there have been some great advances in the realm of concrete additive manufacturing. However, one of the major drawbacks of this fabrication technique is that the elements must be self-supporting during printing. While most other additive manufacturing materials can overcome this by using a secondary printed support...
working paper 2017
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Bos, R. (author), Bierbooms, W.A.A.M. (author)
An important problem in wind turbine design is the prediction of the 50-year load, as set by the IEC 61400-1 Design Load Case (DLC) 1.1. In most cases, designers work with limited simulation budgets and are forced to use extrapolation schemes to obtain the required return level. That this is no easy task is proven by the many studies dedicated...
journal article 2017
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Bos, R.A. (author), Plettenburg, D.H. (author)
The addition of a cosmetic glove to an upper limb prosthesis has a distinct effect on the cosmetic value, but its viscoelastic behaviour adds a substantial amount of stiffness and hysteresis to the system. As a result, the overall usability of the prosthesis is degraded. A novel negative stiffness element is designed to compensate for the...
journal article 2017
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Bos, R.A. (author), Plettenburg, D.H. (author), Herder, J.L. (author)
This study does not describe a success-story. Instead, it describes an exploratory process and the lessons learned while designing a compliant mechanism for a dynamic hand orthosis. Tools from engineering optimization and rapid prototyping techniques were used, with the goal to design a mechanism to compensate for hypertonic or contracted finger...
conference paper 2017
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Evans, Tavia E. (author), O'Sullivan, Michael J. (author), De Groot, Marius (author), Niessen, W.J. (author), Hofman, Albert (author), Krestin, Gabriel P. (author), Van Der Lugt, Aad (author), Portegies, Marileen L P (author), Koudstaal, Peter J. (author), Bos, Daniel (author), Vernooij, Meike W. (author), Ikram, M. Arfan (author)
Background and Purpose - The presence of subclinical vascular brain disease, including white matter lesions and lacunar infarcts, substantially increases the risk of clinical stroke. White matter microstructural integrity is considered an earlier, potentially better, marker of the total burden of vascular brain disease. Its association with...
journal article 2016
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Bos, R.A. (author), Haarman, CJW (author), Stortelder, T. (author), Nizamis, K (author), Herder, J.L. (author), Stienen, AHA (author), Plettenburg, D.H. (author)
The development of dynamic hand orthoses is a fast-growing field of research and has resulted in many different devices. A large and diverse solution space is formed by the various mechatronic components which are used in these devices. They are the result of making complex design choices within the constraints imposed by the application, the...
journal article 2016
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Bos, R. (author), Giyanani, A.H. (author), Bierbooms, W.A.A.M. (author)
Lidars have gained a lot of popularity in the field of wind energy, partly because of their potential to be used for wind turbine control. By scanning the oncoming wind field, any threats such as gusts can be detected early and high loads can be avoided by taking preventive actions. Unfortunately, lidars suffer from some inherent weaknesses that...
journal article 2016
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Bos, R. (author), Veldkamp, D. (author)
An important yet difficult task in the design of wind turbines is to assess the extreme load behaviour, most notably finding the 50-year load. Where existing methods often focus on ways to extrapolate from small sample sizes, this paper proposes a different approach. It combines generating constrained gusts in turbulence fields, Delaunay...
journal article 2016
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Bomer, N. (author), Den Hollander, W.T.H.F. (author), Ramos, Y.F.M. (author), Bos, S.D. (author), Van der Breggen, R. (author), Lakenberg, N. (author), Pepers, B.A. (author), Van Eeden, A.E. (author), Darvishan, A. (author), Tobi, E.W. (author), Duijnisveld, B.J. (author), Van den Akker, E.B. (author), Heijmans, B.T. (author), Van Roon-Mom, W.M.C. (author), Verbeek, F.J. (author), Osch, G.J.V.M. (author), Nelissen, R.G.H.H. (author), Slagboom, P.E. (author), Meulenbelt, I. (author)
Objectives: To investigate how the genetic susceptibility gene DIO2 confers risk to osteoarthritis (OA) onset in humans and to explore whether counteracting the deleterious effect could contribute to novel therapeutic approaches. Methods: Epigenetically regulated expression of DIO2 was explored by assessing methylation of positional CpG...
journal article 2015
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Ikram, M.A. (author), Van der Lugt, A. (author), Niessen, W.J. (author), Koudstaal, P.J. (author), Krestin, G.P. (author), Hofman, A. (author), Bos, D. (author), Vernooij, M.W. (author)
Imaging plays an essential role in research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to elucidate the causes of neurological disease by performing imaging of the brain in a prospective population-based setting. Initially, in 1995 and 1999, random...
journal article 2015
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Bos, R.W. (author)
Stiffened panels at the water line of a ship experience in-plane loads due to ship bending and torsion, as well as out-of-plane loads due to wave impacts. Wave impacts weaken the panel with respect to in-plane loads, but are hard to predict because of complex physics. The in-plane strength of the panel supports the surrounding ship structure....
master thesis 2015
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Bos, R. (author), Bierbooms, W.A.A.M. (author), Van Bussel, G.J.W. (author)
An important problem that arises during the design of wind turbines is estimating extreme loads with sufficient accuracy. This is especially difficult during iterative design phases when computational resources are scarce. Over the years, many methods have been proposed to extrapolate extreme load distributions from relatively short time series...
conference paper 2015
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