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Gautam, K. (author), Roebroeck, M.E. (author), Bogaard, T.A. (author), Blom, A. (author)Rivers flowing from the highlands to the lowlands, characterize the Terai Arc Landscape (TAL) in Nepal and India, but also the neighbouring region in Bhutan. The sudden change in slope results in deposition of nutrient-rich sediment, which forms large alluvial or fluvial fans that enhance biodiversity and economic activities in the region. Our...abstract 2023
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Blom, A. (author), Schielen, R.M.J. (author)Typically the time scale of river response to change of the controls (i.e., flow duration curve, sediment flux, and sea level) is of the order of decades to centuries. Understanding temporal change and, in particular, abrupt change in channel response is increasingly important in engineered river systems, as abrupt change may negatively affect...abstract 2023
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Chowdhury, M. Kifayath (author), Blom, A. (author), Ylla Arbos, C. (author), Schielen, R.M.J. (author)River bifurcations divide the water and sediment over two downstream branches or bifurcates. As the changing climate adjusts the boundary conditions (i.e., base level, hydrograph, and sediment flux) for bifurcations, it will affect their flow and sediment partitioning over the bifurcates. Our objective is to provide insight into the response of...abstract 2023
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Stancanelli, L.M. (author), Dercksen, J.A. (author), Wens, A. (author), Blom, A. (author)A monitoring technique capable of assessing the status of an aquatic ecosystem is needed for reversing negative trends in river biodiversity. Recently, an innovative technique for detecting the degree of biodiversity based on environmental DNA traces (mucus, shed skins etc.) has been proposed (Carraro et al., 2020). This eDNA-based biomonitoring...abstract 2023
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Ylla Arbos, C. (author), Blom, A. (author), Sloff, C.J. (author), Schielen, R.M.J. (author)Climate change puts pressure on river systems, as it increasingly alters the river controls. Engineered rivers with a fixed planform respond to climate change and human intervention by adjusting the channel slope and bed surface grain size distribution. This response often consists of channel bed incision, over hundreds of kilometres, and during...abstract 2023
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Ruiter, Annabel M. (author), Wang, Z. (author), Yin, Zhao (author), Naber, Willemijn C. (author), Simons, Jerrel (author), Blom, Jurre T. (author), van Gemert, J.C. (author), Verschuuren, Jan J.G.M. (author), Tannemaat, M.R. (author)Objective: Myasthenia gravis (MG) is an autoimmune disease leading to fatigable muscle weakness. Extra-ocular and bulbar muscles are most commonly affected. We aimed to investigate whether facial weakness can be quantified automatically and used for diagnosis and disease monitoring. Methods: In this cross-sectional study, we analyzed video...journal article 2023
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Ylla Arbos, C. (author), Blom, A. (author), Sloff, C.J. (author), Schielen, R.M.J. (author)Human intervention makes river channels adjust their slope and bed surface grain size as they transition to a new equilibrium state in response to engineering measures. Climate change alters the river controls through hydrograph changes and sea level rise. We assess how channel response to climate change compares to channel response to human...journal article 2023
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Bongaerts, Michiel (author), Kulkarni, Purva (author), Zammit, Alan (author), Bonte, Ramon (author), Kluijtmans, Leo A. J. (author), Blom, Henk J. (author), Engelke, Udo F. H. (author), Tax, D.M.J. (author), Ruijter, George J.G. (author), Reinders, M.J.T. (author)Untargeted metabolomics (UM) is increasingly being deployed as a strategy for screening patients that are suspected of having an inborn error of metabolism (IEM). In this study, we examined the potential of existing outlier detection methods to detect IEM patient profiles. We benchmarked 30 different outlier detection methods when applied to...journal article 2023
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Blom, Y. (author), Vogt, M.R. (author), Ruiz Tobon, C.M. (author), Santbergen, R. (author), Zeman, M. (author), Isabella, O. (author)The tandem PV technology can potentially increase the efficiency of PV modules over 30%. To design efficient modules, a quantification of the different losses is important. Herein, a model for quantifying the energy loss mechanisms in PV systems under real-world operating conditions with a level of detail back to the components and their...journal article 2023
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Lee, J. (author), Mitici, M.A. (author), Blom, H.A.P. (author), Bieber, Pierre (author), Freeman, Floris (author)The increasing use of on-board sensor monitoring and data-driven algorithms has stimulated the recent shift to data-driven predictive maintenance for aircraft. This paper discusses emerging challenges for data-driven predictive aircraft maintenance. We identify new hazards associated with the introduction of data-driven technologies into...journal article 2023
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Bannenberg, L.J. (author), Blom, Larissa (author), Sakaki, Kouji (author), Asano, Kohta (author), Schreuders, H. (author)Nanostructured metal hydrides could play a key role in a hydrogen economy. The nanostructuring or confinement of these materials as, e.g., thin films significantly affects the structural and functional properties. For tantalum hydride, a versatile hydrogen sensing material, we show that the confinement of tantalum as a thin film extends the...journal article 2023
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Morgana, Florencia (author), Opstelten, Rianne (author), Slot, Manon C. (author), Scott, Andrew M. (author), van Lier, René A.W. (author), Blom, Bianca (author), Mahfouz, A.M.E.T.A. (author), Amsen, Derk (author)CD4+CD25+FOXP3+ regulatory T (Treg) cells control immunological tolerance. Treg cells are generated in the thymus (tTreg) or in the periphery. Their superior lineage fidelity makes tTregs the preferred cell type for adoptive cell therapy (ACT). How human tTreg cells develop is incompletely understood. By combining single-cell transcriptomics...journal article 2022
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- Thewissen, A. (author), Hrachowitz, M. (author), Blom, A. (author) conference paper 2022
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- Ahrendt, S.M. (author), Blom, A. (author), van Denderen, R. Pepijn (author), Schielen, R.M.J. (author), Horner-Devine, Alexander (author) conference paper 2022
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- Dercksen, J.A. (author), Stancanelli, L.M. (author), Blom, A. (author) conference paper 2022
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- Chowdhury, M. Kifayath (author), Blom, A. (author), Ylla Arbos, C. (author), Verbeek, Merel C. (author), Schropp, M.H.I. (author), Schielen, R.M.J. (author) conference paper 2022
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- Czapiga, Matthew (author), Blom, A. (author), Viparelli, Enrica (author) conference paper 2022
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- Ylla Arbos, C. (author), Blom, A. (author), Schielen, R.M.J. (author) conference paper 2022
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Bongaerts, Michiel (author), Bonte, Ramon (author), Demirdas, Serwet (author), Huidekoper, Hidde H. (author), Langendonk, Janneke (author), Wilke, Martina (author), de Valk, Walter (author), Blom, Henk J. (author), Reinders, M.J.T. (author), Ruijter, George J.G. (author)The integration of metabolomics data with sequencing data is a key step towards improving the diagnostic process for finding the disease-causing genetic variant(s) in patients suspected of having an inborn error of metabolism (IEM). The measured metabolite levels could provide additional phenotypical evidence to elucidate the degree of...journal article 2022
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Groot, Stefan (author), Bani, Mirjam (author), Barendregt, Ester (author), Bezemer, Dirk (author), Blom, Marieke (author), Boelhouwer, P.J. (author), Bokeloh, Philip (author)De Nederlandse woningmarkt is slecht toegankelijk, creëert vermogensongelijkheid en is grillig. Dat laatste is schadelijk voor onze economie. Bovendien is het huidige woonbeleid duur. Een grondige renovatie van het woonbeleid biedt een structurele oplossing.journal article 2022