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de Boer, Bas (author), Strasser, C. (author), Mulder, S.S. (author)Medicine is increasingly focusing on the prevention of diseases. The digital twin (DT) is considered to be an important technological development for realizing this transition. Broadly speaking, a DT is an in silico representation of an individual that dynamically reflects molecular and physiological status, which makes it possible to monitor...journal article 2022
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- de Boer, J.J. (author) book chapter 2022
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- Cavallo, R. (author), de Boer, J.J. (author), Berlingieri, F. (author), Corradi, Emilia (author) book chapter 2022
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de Boer, L.E. (author), Mouter, N. (author), de Vries, M.O. (author)Brede welvaart betekent breder naar vooruitgang kijken dan in termen van economische groei of – in het mobiliteitsdomein – capaciteitsknelpunten alleen. De behoefte aan een brede welvaart benadering resoneert in toenemende mate bij professionals, beleidsmakers en politici. Het oude verhaal is als een jas die om meerdere redenen steeds minder...conference paper 2022
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Schifferstein, Hendrik N.J. (author), Lemke, M. (author), de Boer, Alie (author)Commercial food packages may contain multiple messages. Packaging designers try to integrate all messages into a coherent design. Designers may use text, images or stylistic features, but these mediums may differ in their suitability to communicate specific product benefits. To evaluate the usefulness and effectiveness of these three mediums,...journal article 2022
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de Boer, Maaike H.T. (author), Vethman, Steven (author), Bakker, R.M.B. (author), Adhikari, Ajaya (author), Marcus, Michiel (author), de Greeff, Joachim (author), van der Waa, J.S. (author), van Zoelen, E.M. (author), Kamphorst, Bart (author)The goal of the FATE system is decision support with use of state-of-the-art human-AI co-learning, explainable AI and fair, secure and privacy-preserving usage of data. This AI-based support system is a general system, in which the modules can be tuned to specific use cases. The FATE system is designed to address different user roles, such as...journal article 2022
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Nuijens, Louise (author), Savazzi, A.C.M. (author), de Boer, G. (author), Brilouet, P. E. (author), George, G. (author), Lothon, M. (author), Zhang, D. (author)Profiles of eddy momentum flux divergence are calculated as the residual in the momentum budget constructed from airborne circular dropsonde arrays ((Formula presented.) 220 km) for 13 days during the EUREC (Formula presented.) A/ATOMIC field campaign. The observed dynamical forcing averaged over all flights agrees broadly with European...journal article 2022
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de Boer, Bas (author), Kudina, O. (author)In this paper, we examine the qualitative moral impact of machine learning-based clinical decision support systems in the process of medical diagnosis. To date, discussions about machine learning in this context have focused on problems that can be measured and assessed quantitatively, such as by estimating the extent of potential harm or...journal article 2022
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Sharifi, S. (author), Luft, F. (author), de Boer, L. (author), Buijink, A. W.G. (author), Mugge, W. (author), Schouten, A.C. (author), Heida, T. (author), Bour, L. J. (author), van Rootselaar, A. F. (author)Tremor is thought to be an effect of oscillatory activity within the sensorimotor network. To date, the underlying pathological brain networks are not fully understood. Disentangling tremor activity from voluntary motor output and sensorimotor feedback systems is challenging. To better understand the intrinsic sensorimotor fingerprint...journal article 2022
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Ho, Loan (author), de Boer, Victor (author), van Riemsdijk, M.B. (author), Schlobach, Stefan (author), Tielman, M.L. (author)Hybrid Intelligence (HI) is the combination of human and machine intelligence, expanding human intellect instead of replacing it. Information in HI scenarios is often inconsistent, e.g. due to shifting preferences, user's motivation or conflicts arising from merged data. As it provides an intuitive mechanism for reasoning with conflicting...journal article 2022
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Lemke, M. (author), de Boer, Bas (author)Disgust is commonly understood as an emotion of aversion. However, people seem to eat certain food items not despite containing disgust eliciting features but because of them. In this paper, we introduce the term aesthetic disgust to capture this phenomenon. We outline in our manuscript how designers use different techniques to stage the food...journal article 2022
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van Calcar, C.J. (author), de Boer, Bas (author), Blank, B. (author), van de Wal, Roderik S W (author), van der Wal, W. (author)The Earth’s surface and interior deform due to a changing load of the Antarctic Ice Sheet (AIS) during the last glacial cycle, called Glacial Isostatic Adjustment (GIA). This deformation changes the surface height of the ice sheet and indirectly the groundling line position. These changes in surface height and grounding line position influence...abstract 2021
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- van Koningsveld, M. (author), Lansen, A.J. (author), de Boer, T.M. (author), Quist, P. (author), de Boom, L. (author), Taneja, P. (author), de Vriend, H.J. (author) book chapter 2021
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Yang, Y. (author), de Boer, Ane (author), den Uijl, J.A. (author)A recent contest of shear tests modelling was carried out in 2019. Teams from universities and consultancies around Europe were invited to predict the shear capacity of two reinforced concrete beams. The basics of the numerical models were to be set up according the Dutch NLFEM Guideline RTD 1016–1:2017. In the contest, two reinforced...journal article 2021
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de Boer, Bas (author), Lemke, M. (author)Obesity has been pointed out as one of the main current health risks leading to calls for a so-called “war on obesity”. As we show in this paper, activities that attempt to counter obesity by persuading people to adjust a specific behavior often employ a pedagogy of regret and disgust. Nowadays, however, public healthcare campaigns that aim to...journal article 2021
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- van Muijden, Jaap (author), Stepchuk, I. (author), de Boer, A.I. (author), Kogenhop, O. (author), Rademaker, E.R. (author), van der Sman, E.S. (author), Kos, J. (author), Posada Duque, J.A. (author), Palmeros Parada, M.D.M. (author) report 2021
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Wiegel, M.F. (author), de Boer, W.P. (author), van Koningsveld, M. (author), van der Hout, A.J. (author), Reniers, A.J.H.M. (author)Seaport operability is key to the economic viability of ports. Metocean conditions (e.g., wind, short waves, and infragravity waves) affect this operability when certain thresholds are exceeded. This paper describes a method for the global mapping of seaport operability risk indicators using open-source metocean data. This global-scale...journal article 2021
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Maduro, L.A. (author), de Boer, Charles (author), Zuiddam, M.R. (author), Memisevic, E. (author), Conesa Boj, S. (author)We report on the fabrication of molybdenum (Mo) nanopillar (NP) arrays with NP diameters down to 75 nm by means of deep-reactive ion etching at cryogenic temperatures. A variable-thickness Mo metal layer sputtered onto a Si<sub>3</sub>N<sub>4</sub>/Si substrate makes possible NPs with different lengths in a controllable manner. We demonstrate...journal article 2021
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Optical tissue measurements of invasive carcinoma and ductal carcinoma in situ for surgical guidancede Boer, Lisanne L. (author), Kho, Esther (author), Van de Vijver, Koen K. (author), Vranken Peeters, Marie Jeanne T.F.D. (author), van Duijnhoven, Frederieke (author), Hendriks, B.H.W. (author), Sterenborg, Henricus J.C.M. (author), Ruers, Theo J.M. (author)Background: Although the incidence of positive resection margins in breast-conserving surgery has decreased, both incomplete resection and unnecessary large resections still occur. This is especially the case in the surgical treatment of ductal carcinoma in situ (DCIS). Diffuse reflectance spectroscopy (DRS), an optical technology based on...journal article 2021
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Srinivasa Raja, A. (author), de Boer, Pascal (author), Giepmans, Ben N.G. (author), Hoogenboom, J.P. (author)Electron microscopy is crucial for imaging biological ultrastructure at nanometer resolution. However, electron irradiation also causes specimen damage, reflected in structural and chemical changes that can give rise to alternative signals. Here, luminescence induced by electron-beam irradiation is reported across a range of materials widely...journal article 2021