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van Gemert, Y. (author), Kozijn, A. E. (author), Pouwer, M. G. (author), Kruisbergen, N. N.L. (author), van den Bosch, M. H.J. (author), Blom, A.B. (author), Pieterman, E. J. (author), Weinans, Harrie (author), Stoop, R. (author), Princen, H. M.G. (author), van Lent, P. L.E.M. (author)Objective: High systemic cholesterol levels have been associated with osteoarthritis (OA) development. Therefore, cholesterol lowering by statins has been suggested as a potential treatment for OA. We investigated whether therapeutic high-intensive cholesterol-lowering attenuated OA development in dyslipidemic APOE∗3Leiden.CETP mice. Methods:...journal article 2021
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Zeng, X. (author), Blom, A. (author), Czapiga, Matthew J. (author), An, Chenge (author), Parker, Gary (author), Fu, Xudong (author)For upland ephemeral gullies, gully erosion is strongly related to the formation and migration of cyclic steps. It is necessary to provide insight into the process of cyclic step development to accurately predict the pace of landscape evolution and soil loss. Information on the geometry of cyclic steps in subaerial environments is limited,...journal article 2021
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Margaritis, Alexandros (author), Pipintakos, Georgios (author), Varveri, Aikaterini (author), Jacobs, Geert (author), Hasheminejad, Navid (author), Blom, Johan (author), Van den bergh, Wim (author)The fatigue resistance, as a performance indicator, is of paramount importance for the selection and benchmarking of bituminous materials. The bituminous mortar can be considered as the medium that connects and envelopes the coarse aggregate skeleton, and hence will significantly influence the fatigue resistance at bulk-scale. Therefore this...journal article 2021
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Jansen, J.D. (author), Blom, J.C. (author), Free, Renske (author), Kouwenhoven, Paula (author), Fokkema, J.T. (author), de Bruijn, Birgit (author), Smeulders, Julien (author), Drenth, D.J.H. (author), van der Kleijn, Piet Hein (author)This booklet provides additional information to the work of art 'Soft Layer' located in front of the faculty of Civil Engineering and Geosciences. This piece of art is an initiative of students and alumni of the Mijnbouwkundige Vereeniging and has been revealed on the 24th of February, 2020.other 2020
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van de Vyver, Ighor (author), Harvey-Scholes, Calum (author), Hoggett, Richard (author), Hoppe, T. (author), Jansen, S.C. (author), Fremouw, M.A. (author), Blom, Tess (author), Itten, A.V. (author), Pauvert, Alexandre (author)SHIFFT is an Interreg 2 Seas project, running from 2019-2022, promoting cross-border cooperation between 4 European countries: The Netherlands, France, Belgium and The United Kingdom. It has been approved under the priority ‘Low Carbon Technologies’.report 2020
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Abate, Alessandro (author), Blom, H.A.P. (author), Cauchi, Nathalie (author), Delicaris, Joanna (author), Hartmanns, Arnd (author), Khaled, Mahmoud (author), Lavaei, Abolfazl (author), Pilch, Carina (author), Remke, Anne (author)This report presents the results of a friendly competition for formal verification and<br/>policy synthesis of stochastic models. It also introduces new benchmarks within this<br/>category, and recommends next steps for this category towards next year's edition of the competition. The friendly competition took place as part of the workshop...conference paper 2020
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Ylla Arbos, C. (author), Blom, A. (author), Acevedo Goldaracena, F. (author), van Vuren, S (author), Schielen, R.M.J. (author)The Rhine reach comprising the Niederrhein and the Upper Rhine Delta is characterized by a long history of engineering interventions. The area is densely populated and the Rhine, the main inland waterway in Europe, justifying the need for such measures. Interventions have had a strong impact on morphodynamic channel characteristics. We use bed...conference paper 2020
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Bongaerts, Michiel (author), Bonte, Ramon (author), Demirdas, Serwet (author), Jacobs, Edwin H. (author), Oussoren, Esmee (author), van der Ploeg, Ans T. (author), Wagenmakers, Margreet A.E.M. (author), Hofstra, Robert M.W. (author), Blom, Henk J. (author), Reinders, M.J.T. (author), Ruijter, George J.G. (author)Untargeted metabolomics is an emerging technology in the laboratory diagnosis of inborn errors of metabolism (IEM). Analysis of a large number of reference samples is crucial for correcting variations in metabolite concentrations that result from factors, such as diet, age, and gender in order to judge whether metabolite levels are abnormal....journal article 2020
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Rattanagraikanakorn, B. (author), Blom, H.A.P. (author), Sharpanskykh, Alexei (author), de Wagter, C. (author), Jiang, C. (author), Schuurman, M.J. (author), Gransden, Derek I. (author), Happee, R. (author)Evaluating safety risk posed to third parties on the ground due to UAS impact requires a model of probability of fatality (PoF) for human. For quadrotor UAS, the existing impact models predict remarkably different PoFs. The most pessimistic is the impact model adopted by Range Commanders Council (RCC) while the Blunt Criterion model is far...conference paper 2020
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Jiang, C. (author), Blom, H.A.P. (author), Sharpanskykh, Alexei (author)Use of Unmanned Aircraft Systems (UAS) is growing rapidly around the world. Very different types of UAS are used for applications such as aerial photography, inspection, emergency and Urban Air Mobility (UAM), operating in low altitude and urban environment, as well as in high altitude airspace integrated with the conventional air transportation...conference paper 2020
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Rattanagraikanakorn, B. (author), Schuurman, M.J. (author), Gransden, Derek I. (author), Happee, R. (author), de Wagter, C. (author), Sharpanskykh, Alexei (author), Blom, H.A.P. (author)Recent developments in the concept of UAS operations in urban areas have led to risk concerns of UAS collision with human. To better understand this risk, head and neck injuries due to UAS collisions have been investigated by different research teams using crash dummies. Because of the limitations in biofidelity of a crash dummy, head injury...journal article 2020
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Stroeve, Sybert H. (author), Blom, H.A.P. (author), Medel, Carlos Hernandez (author), Daroca, Carlos Garcia (author), Cebeira, Alvaro Arroyo (author), Drozdowski, Stanislaw (author)Airborne collision avoidance systems (ACASs) form a key safety barrier by providing last-moment resolution advisories (RAs) to pilots for avoiding midair collisions. Intrinsic uncertainties, such as noise in ACAS input signals and variability in pilot performance, imply that the generation of RAs and the effectuated aircraft trajectories are...journal article 2020
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Hunink, Yvo Thomas Anton (author), Kamp, L.M. (author), Blom, E.M. (author)Energy system projects in countries like India are often failing. Not only because of technical or economical barriers, but mainly institutional and social issues are at the base of these failures. A co-creation, or participatory, process to align all demands and requirements of the different stakeholders is required. This paper takes...conference paper 2020
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Sun, Junzi (author), Blom, H.A.P. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)This article investigates the estimation of aircraft mass and thrust settings of departing aircraft using a recursive Bayesian method called particle filtering. The method is based on a nonlinear state-space system derived from aircraft point-mass performance models. Using only aircraft surveillance data, flight states such as position,...journal article 2019
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Chen, B. (author), Sun, Yubo (author), Jacquemin, Loic (author), Zhang, Shizhe (author), Blom, Kees (author), Lukovic, M. (author), Ye, G. (author)At present, most municipal solid waste incineration (MSWI) bottom ash, as being disposed of as waste, is directly landfilled, raising concern about the environmental issue and potential loss of resources. Given that the natural raw materials used for cement production are being depleted, the recycling of MSWI bottom ash for the application as...conference paper 2019
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Arkesteijn, L. (author), Blom, A. (author), Czapiga, Matthew J. (author), Chavarrias Borras, V. (author), Labeur, R.J. (author)An engineered alluvial river (i.e., a fixed-width channel) has constrained planform but is free to adjust channel slope and bed surface texture. These features are subject to controls: the hydrograph, sediment flux, and downstream base level. If the controls are sustained (or change slowly relative to the timescale of channel response), the...journal article 2019
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Rattanagraikanakorn, B. (author), Gransden, Derek I. (author), Schuurman, M.J. (author), de Wagter, C. (author), Happee, R. (author), Sharpanskykh, Alexei (author), Blom, H.A.P. (author)Understanding the impact severity of unmanned aircraft system (UAS) collisions with the human body remains a challenge and is essential to the development of safe UAS operations. Complementary to performing experiments of UAS collisions with a crash dummy, a computational impact model is needed in order to capture the large variety of UAS types...journal article 2019
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Chavarrias Borras, V. (author), Arkesteijn, L. (author), Blom, A. (author)The active layer model (Hirano, 1971) is frequently used for modeling mixed-size sediment river morphodynamic processes. It assumes that all the dynamics of the bed surface are captured by a homogeneous top layer that interacts with the flow. Although successful in reproducing a wide range of phenomena, it has two problems: (1) It may become...journal article 2019
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Abate, Alessandro (author), Blom, H.A.P. (author), Cauchi, Nathalie (author), Degiorgio, Kurt (author), Franzle, Martin (author), Hahn, Ernst Moritz (author), Haesaert, Sofie (author), Ma, H. (author), Oishi, Meeko (author)This report presents the results of a friendly competition for formal verification and policy synthesis of stochastic models. It also introduces new benchmarks within this category, and recommends next steps for this category towards next year’s edition of the competition. The friendly competition took place as part of the workshop Applied...conference paper 2019
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Ye, G. (author), Lukovic, M. (author), Ghiassi, B. (author), Aldin, Zainab (author), Prinsse, Silke (author), Liu, Jonh (author), Nedeljković, Marija (author), Hordijk, D.A. (author), Lagendijk, P. (author), Bosman, A. (author), Blom, T.A. (author), van Leeuwen, M. (author), Huang, Zhekang (author), Celada, Ulric (author), Du, C. (author), van den Berg, J.A.M. (author), Thijssen, A. (author), Wijte, Simon (author)The sustainability of infrastructure projects is becoming increasingly important issue in engineering practice. This means that in the future the construction materials will be selected on the basis of the contribution they can make to reach sustainability requirements. Geopolymers are materials based on by-products from industries. By using...journal article 2019