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Pasma, J.H. (author), Boonstra, T.A. (author), van Kordelaar, J. (author), Spyropoulou, V. (author), Schouten, A.C. (author)Balance control models are used to describe balance behavior in health and disease. We identified the unique contribution and relative importance of each parameter of a commonly used balance control model, the Independent Channel (IC) model, to identify which parameters are crucial to describe balance behavior. The balance behavior was expressed...journal article 2017
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Forbes, P.A. (author), de Bruijn, E. (author), Nijmeijer, SWR (author), Koelman, JHTM (author), van der Helm, F.C.T. (author), Schouten, A.C. (author), Tijssen, MAJ (author), Happee, R. (author)Background Effective sensorimotor integration is essential to modulate (adapt) neck stabilization strategies in response to varying tasks and disturbances. This study evaluates the hypothesis that relative to healthy controls cervical dystonia patients have an impaired ability to modulate afferent feedback for neck stabilization with changes...journal article 2017
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Melskens, J. (author), Eijt, S.W.H. (author), Schouten, M. (author), Vullers, A.S. (author), Mannheim, Awital (author), Schut, H. (author), Macco, Bart (author), Zeman, M. (author), Smets, A.H.M. (author)The nanostructure of hydrogenated amorphous silicon (a-Si:H) is studied by means of doppler broadening positron annihilation spectroscopy (DB-PAS) and Fourier transform infrared (FTIR) spectroscopy. The evolution of open volume deficiencies is monitored during annealing, demonstrating that small vacancies and other small vacancy clusters that...journal article 2017
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Wu, Y. (author), Nieuwenhoff, M.D. (author), Huygen, F.J.P.M. (author), van der Helm, F.C.T. (author), Niehof, S.P. (author), Schouten, A.C. (author)Small nerve fibers regulate local skin blood flow in response to local thermal perturbations. Small nerve fiber function is difficult to assess with classical neurophysiological tests. In this study, a vasomotor response model in combination with a heating protocol was developed to quantitatively characterize the control mechanism of small...journal article 2017
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Vlaar, M.P. (author), Solis Escalante, T. (author), Vardy, A.N. (author), van der Helm, F.C.T. (author), Schouten, A.C. (author)Cortical responses to continuous stimuli as recorded using either magneto- or electroencephalography (EEG) have shown power at harmonics of the stimulated<br/>frequency, indicating nonlinear behavior. Even though the selection of analysis techniques depends on the linearity of the system under study, the importance of nonlinear contributions to...journal article 2017
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Vlaar, M.P. (author), Solis Escalante, T. (author), Dewald, J.P.A. (author), Van Wegen, Erwin E H (author), Schouten, A.C. (author), Kwakkel, G. (author), van der Helm, F.C.T. (author)Background: Cortical damage after stroke can drastically impair sensory and motor function of the upper limb, affecting the execution of activities of daily living and quality of life. Motor impairment after stroke has been thoroughly studied, however sensory impairment and its relation to movement control has received less attention. Integrity...journal article 2017
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Yang, Y. (author), Guliyev, Bekir (author), Schouten, A.C. (author)Mechanical perturbations applied to the wrist joint typically evoke a stereotypical sequence of cortical and muscle responses. The early cortical responses (<100 ms) are thought be involved in the “rapid” transcortical reaction to the perturbation while the late cortical responses (>100 ms) are related to the “slow” transcortical reaction....journal article 2017
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Pasma, J.H. (author), van Kordelaar, J. (author), de Kam, D. (author), Weerdesteyn, V. (author), Schouten, A.C. (author), van der Kooij, H. (author)Background: Closed loop system identification (CLSIT) is a method to disentangle the contribution of underlying systems in standing balance. We investigated whether taking into account lower leg muscle activation in CLSIT could improve the reliability and accuracy of estimated parameters identifying the underlying systems. Methods: Standing...journal article 2017
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Yang, Y. (author), Dewald, J.P.A. (author), van der Helm, F.C.T. (author), Schouten, A.C. (author)Neural coupling between the central nervous system and the periphery is essential for the neural control of movement. Corticomuscular coherence is a popular linear technique to assess synchronised oscillatory activity in the sensorimotor system. This oscillatory coupling originates from ascending somatosensory feedback and descending motor...journal article 2017
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Severson, Tesa M. (author), Wolf, Denise M. (author), Yau, Christina (author), Peeters, Justine (author), Wehkam, Diederik (author), Schouten, Philip C. (author), Chin, Suet-Feung (author), Majewski, Ian J. (author), Michaut, Magali (author), Bosma, Astrid (author), Pereira, Bernard (author), Bismeijer, Tycho (author), Wessels, L.F.A. (author), Caldas, Carlos (author), Bernards, Rene (author), Simon, Iris M. (author), Glas, Annuska M. (author), Linn, Sabine C. (author), van 't Veer, Laura (author)Background: Patients with BRCA1-like tumors correlate with improved response to DNA double-strand break-inducing therapy. A gene expression-based classifier was developed to distinguish between BRCA1-like and non-BRCA1-like tumors. We hypothesized that these tumors may also be more sensitive to PARP inhibitors than standard treatments. Methods:...journal article 2017
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Forbes, P.A. (author), Vlutters, M (author), Dakin, CJ (author), van der Kooij, H. (author), Blouin, JS (author), Schouten, A.C. (author)During walking, the vestibular influence on locomotor activity is phase-dependent and modulated in both limbs with changes in velocity. It is unclear, however, whether this bilateral modulation is due to a coordinated mechanism between both limbs or instead through limb-specific processes that remain masked by the symmetric nature of locomotion....journal article 2017
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Rol, M.A. (author), Bultink, C.C. (author), O'Brien, T.E. (author), De Jong, S. R. (author), Theis, L. S. (author), Fu, X. (author), Lüthi, F. (author), Vermeulen, R.F.L. (author), de Sterke, J.C. (author), Bruno, A. (author), Deurloo, D. (author), Schouten, R.N. (author), Wilhelm, FK (author), DiCarlo, L. (author)We present a tuneup protocol for qubit gates with tenfold speedup over traditional methods reliant on qubit initialization by energy relaxation. This speedup is achieved by constructing a cost function for Nelder-Mead optimization from real-time correlation of nondemolition measurements interleaving gate operations without pause. Applying the...journal article 2017
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Wang, M. (author), Becker, T. (author), Schouten, Bob (author), Vlugt, T.J.H. (author), Infante Ferreira, C.A. (author)To use high-temperature waste heat generated by diesel engines for onboard refrigeration of fishing vessels, an ammonia-based double-effect vapor absorption refrigeration cycle is proposed. Non-volatile ionic liquids are applied as absorbents in the double-effect absorption system. In comparison to systems using ammonia/water fluid, the...journal article 2018
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Vlaar, M.P. (author), Birpoutsoukis, Georgios (author), Lataire, John (author), Schouten, A.C. (author), Schoukens, Johan (author), van der Helm, F.C.T. (author)Joint manipulation elicits a response from the sensors in the periphery which, via the spinal cord, arrives in the cortex. The average evoked cortical response recorded using electroencephalography was shown to be highly nonlinear; a linear model can only explain 10% of the variance of the evoked response, and over 80% of the response is...journal article 2018
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Pasma, J.H. (author), Assländer, Lorenz (author), van Kordelaar, J. (author), de Kam, Digna (author), Mergner, Thomas (author), Schouten, A.C. (author)The Independent Channel (IC) model is a commonly used linear balance control model in the frequency domain to analyze human balance control using system identification and parameter estimation. The IC model is a rudimentary and noise-free description of balance behavior in the frequency domain, where a stable model representation is not...journal article 2018
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Heerema, S.J. (author), Vicarelli, L. (author), Pud, S. (author), Schouten, R.N. (author), Zandbergen, H.W. (author), Dekker, C. (author)Many theoretical studies predict that DNA sequencing should be feasible by monitoring the transverse current through a graphene nanoribbon while a DNA molecule translocates through a nanopore in that ribbon. Such a readout would benefit from the special transport properties of graphene, provide ultimate spatial resolution because of the single...journal article 2018
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Filatova, O.G. (author), van Vliet, L.J. (author), Schouten, A.C. (author), Kwakkel, Gert (author), van der Helm, F.C.T. (author), Vos, F.M. (author)Better insight into white matter (WM) alterations after stroke onset could help to understand the underlying recovery mechanisms and improve future interventions. MR diffusion imaging enables to assess such changes. Our goal was to investigate the relation of WM diffusion characteristics derived from diffusion models of increasing complexity...journal article 2018
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Fu, X. (author), Rol, M.A. (author), Bultink, C.C. (author), van Someren, J. (author), Khammassi, N. (author), Ashraf, I. (author), Vermeulen, R.F.L. (author), de Sterke, J.C. (author), Vlothuizen, W.J. (author), Schouten, R.N. (author), Almudever, Carmen G. (author), DiCarlo, L. (author), Bertels, K.L.M. (author)This article proposes a quantum microarchitecture, QuMA. Flexible programmability of a quantum processor is achieved by multilevel instructions decoding, abstracting analog control into digital control, and translating instruction execution with non-deterministic timing into event trigger with precise timing. QuMA is validated by several...journal article 2018
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van Kordelaar, J. (author), Pasma, J.H. (author), Cenciarini, Massimo (author), Schouten, A.C. (author), van der Kooij, H. (author), Maurer, Christoph (author)The vestibular system is involved in gaze stabilization and standing balance control. However, it is unclear whether vestibular dysfunction affects both processes to a similar extent. Therefore, the objective of this study was to determine how the reliance on vestibular information during standing balance control is related to gaze...journal article 2018
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van de Ruit, M.L. (author), Cavallo, Gaia (author), Lataire, John (author), van der Helm, F.C.T. (author), Mugge, W. (author), van Wingerden, J.W. (author), Schouten, A.C. (author)During movements, humans continuously regulate their joint impedance to minimize control effort and optimize performance. Joint impedance describes the relationship between a joint's position and torque acting around the joint. Joint impedance varies with joint angle and muscle activation and differs from trial-to-trial due to inherent...journal article 2018