Engineering an artificial catch bond using mechanical anisotropy

Catch bonds are a rare class of protein-protein interactions where the bond lifetime increases under an external pulling force. Here, we report how modification of anchor geometry generates catch bonding behavior for the mechanostable Dockerin G:Cohesin E (DocG:CohE) adhesion complex found on human gut bacteria. Using AFM single-molecule...

Modelling the combined impact of sea level rise, land subsidence, and tropical cyclones in compound flooding of coastal cities

Low-lying coastal areas are threatened worldwide by compound flooding effects, including sea-level rise (SLR), frequent tropical cyclones (TCs), and accelerated land subsidence (LS). Compound flooding results in a negative effect, creating challenges for decision-making and coastal management for sustainable urban development. To comprehend...

Role of thermodynamic relaxation on effectiveness of recycling agents on properties of aged bitumen

The low-temperature relaxation and fatigue cracking performance are two essential aspects in estimating the rejuvenation efficiency of recycling agents (RAs). This study aims to fundamentally investigate the effects of recycling agent type/dosage and aging degree of bitumen on thermodynamic and rheological properties of rejuvenated bitumen at...

A Thermoelectric Energy Harvesting System Assisted by A Piezoelectric Transducer Achieving 10-mV Cold-Startup and 82.7% Peak Efficiency

This article presents a 10mV-startup-voltage thermoelectric energy harvesting system, assisted by a piezoelectric generator (PEG) as a cold starter. It exploits the fact that when a thermoelectric energy harvesting system is implemented in a place where kinetic energy is also present, the PEG starter can provide a clock signal to start the...

Multi Physics Simulation of Wafer Bonding with Nano Copper Paste

The significance of wafer bonding is fundamental to the progression of electronic systems. Common fabrication techniques for Cu pillars play a crucial role in establishing resilient and efficient interconnects within semiconductor devices. It is imperative to explore the potential of nano-copper as an alternative material to overcome limitations...

Construction of AlGaN/GaN high-electron-mobility transistor-based biosensor for ultrasensitive detection of SARS-CoV-2 spike proteins and virions

The COVID-19 pandemic has highlighted the need for rapid and sensitive detection of SARS-CoV-2. Here, we report an ultrasensitive SARS-CoV-2 immunosensor by integration of an AlGaN/GaN high-electron-mobility transistor (HEMT) and anti-SARS-CoV-2 spike protein antibody. The AlGaN/GaN HEMT immunosensor has demonstrated the capability to detect...

Simulation of Nanoparticle Agglomerate Fluidization Based on Continuum Theory of Cohesive Particles

Nanoparticles are usually fluidized as agglomerates, which are in dynamic states of agglomeration and fragmentation. It is critical to consider the size distribution of agglomerates in modeling of the fluidization of nanoparticle agglomerates. In this article, the fluidization behavior of nanoparticle agglomerates is investigated using a two...

Investigating the Sintering Process and Mechanical Properties of Nano-copper Particles Coupling Particle Packing Modeling with Molecular Dynamics Simulation

The nano-copper particles are widely used in the sintering processes of packaging wide bandgap semiconductors. Despite the significant success in the industry, the mechanism bridging the sintering process to the mechanical properties of sintered nano-copper is not yet well-modeled. In this paper, the impacts of different sintering temperatures...

Ultrasmall Gold Nanoparticles Radiolabeled with Iodine-125 as Potential New Radiopharmaceutical

The relatively high linear energy transfer of Auger electrons, which can cause clustered DNA damage and hence efficient cell death, makes Auger emitters excellent candidates for attacking metastasized tumors. Moreover, gammas or positrons are usually emitted along with the Auger electrons, providing the possibility of theragnostic...

Advancing the local climate zones framework: A critical review of methodological progress, persisting challenges, and future research prospects

The local climate zones (LCZs) classification system has emerged as a more refined method for assessing the urban heat island (UHI) effect. However, few researchers have conducted systematic critical reviews and summaries of the research on LCZs, particularly regarding significant advancements of this field in recent years. This paper aims to...

Interoperable Protection and control of multi-terminal HVDC systems

The MMC-based MTDC systems are considered a promising solution for long-distance power transmission, integration of renewable energy sources, and interconnection of power grids. Nowadays, MMC-based MTDC systems have been successfully developed in various projects worldwide and are expected to play a significant role in future electrical power...

Multi-Modelling of the Managed Aquifer Recharge Systems for Sustainable Groundwater Development in Beijing Plain, China

This study explores the challenge of groundwater depletion in the Beijing Plain, a problem exacerbated by rapid socio-economic expansion and unsustainable groundwater abstraction. The core of this research is the development and application of multi-scale numerical groundwater flow and transport models to rigorously evaluate the measures...