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Hoekstra, Mirjam E. (author), Slagter, Maarten (author), Urbanus, Jos (author), Toebes, Mireille (author), Slingerland, Nadine (author), de Rink, Iris (author), Kluin, Roelof J.C. (author), Nieuwland, Marja (author), Wessels, L.F.A. (author)Cells in the tumor microenvironment (TME) influence each other through secretion and sensing of soluble mediators, such as cytokines and chemokines. While signaling of interferon γ (IFNγ) and tumor necrosis factor α (TNFα) is integral to anti-tumor immune responses, our understanding of the spatiotemporal behavior of these cytokines is...journal article 2024
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Croon, T.M. (author), Hoekstra, J.S.C.M. (author), Elsinga, M.G. (author), Dalla Longa, F. (author), Mulder, Peter (author)Recent energy price spikes have led to increased energy poverty among low-income households living in inefficient homes. Accurate statistics on energy poverty help inform resource allocation and better target relief schemes and retrofit funds. Existing indicators are predominantly defined in terms of a headcount ratio – the share of population...journal article 2023
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Groot, D.J. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)Conventional Air Traffic Control is still predominantly being done by human Air Traffic Controllers, however, as the traffic density increases, the workload of the controllers increases as well. Especially for the area of unmanned aviation, driven by the rise in drones, having human controllers might become unfeasible. One of the methods that...journal article 2024
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Groen, Brenda (author), van der Voordt, Theo (author), Hoekstra, B.S. (author), van Sprang, Hester (author)Purpose: This paper aims to explore the relationship between satisfaction with buildings, facilities and services and perceived productivity support and to test whether the findings from a similar study of Batenburg and Van der Voordt (2008) are confirmed in a repeat study after 10 years with more recent data. Design/methodology/approach:...journal article 2019
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Patrinopoulou, Niki (author), Daramouskas, Ioannis (author), Badea, Calin Andrei (author), Morfin Veytia, A. (author), Lappas, Vaios (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author), Kostopoulos, Vassilios (author)Unmanned Aircraft Systems (UAS) Traffic Management (UTM) is an active research subject as its proposed applications are increasing. UTM aims to enable a variety of UAS operations, including package delivery, infrastructure inspection, and emergency missions. That creates the need for extensive research on how to incorporate such traffic, as...journal article 2023
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Morfin Veytia, A. (author), Badea, C. (author), Patrinopoulou, Niki (author), Daramouskas, Ioannis (author), Ellerbroek, Joost (author), Lappas, Vaios (author), Kostopoulos, Vassilios (author), Hoekstra, J.M. (author)The interest in urban air mobility as a potential solution for urban congestion is steadily growing. Air operations in urban areas can present added complexity as compared with traditional air traffic management. As a result, it is necessary to test and develop novel airspace designs and rules. As airspace in urban areas is a scarce resource,...journal article 2023
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Appel-Meulenbroek, Rianne (author), Voulon, Thijs (author), Bergefurt, Lisanne (author), Arkesteijn, M.H. (author), Hoekstra, B.S. (author), der Schaaf, Pity Jongens Van (author)BACKGROUND: During the COVID-19 pandemic, office workers were obliged to work from home (WFH). Alongside known positive aspects of home-based telework, it is associated with reduced health and productivity impacts. Its success depends on employee and environmental characteristics. OBJECTIVE: This paper fills the gap in knowledge on the...journal article 2023
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Dol, C.P. (author), Mazo, Estrella Cruz (author), Lambea Llop, N. (author), Hoekstra, J.S.C.M. (author), Cano Fuentes, G.I. (author), Etxarri, Aitziber Etxezarreta (author)The Spanish home ownership sector has been hit hard by the economic crisis. Repossessions stand at around half a million in the period from 2008 to 2014. This article investigates how the authorities, both at the level of the Spanish state and of the autonomous communities (regions), have responded to this problem. We investigated whether...journal article 2016
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Pietra, F. (author), De Trizio, L. (author), Hoekstra, Anne W. (author), Renaud, N. (author), Prato, Mirko (author), Grozema, F.C. (author), Baesjou, Patrick J. (author), Koole, Rolf (author), Manna, L. (author), Houtepen, A.J. (author)Colloidal quantum dots (QDs) show great promise as LED phosphors due to their tunable narrow-band emission and ability to produce high-quality white light. Currently, the most suitable QDs for lighting applications are based on cadmium, which presents a toxicity problem for consumer applications. The most promising cadmium-free candidate QDs...journal article 2016
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Analysis of Airspace Structure and Capacity for Decentralized Separation Using Fast-Time SimulationsSunil, E. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author), Arntzen, M. (author)The work that is presented in this paper is part of an ongoing study on the relationship between airspace structure and capacity. The present paper investigates the degree of structuring needed to maximize capacity for decentralized en-routeairspace. To this end, four decentralized en-route airspace concepts,...journal article 2017
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Hoekstra, J.S.C.M. (author), Marais, L (author)Subsidised housing often creates a segmented housing market, with some home owners falling into a gap between the subsidised and non-subsidised types. This gap particularly affects middle-income buyers, whose income may be too high to qualify for subsidy but too low to buy a non-subsidised house. Western Europe has policies and affordable...journal article 2016
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Nijhuis, S. (author), Stolk, E.H. (author), Hoekstra, M.J. (author)The Department of Urbanism at the Faculty of Architecture and Built Environment at the Delft University of Technology has a long tradition in educating generations of internationally oriented designers, planners and researchers in urbanism. Here the domain of urbanism is defined as an interdisciplinary approach that engages in real-world...journal article 2016
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Poot, Vincent (author), Hoekstra, M. (author), Geleijnse, M.A.A. (author), van Loosdrecht, Mark C.M. (author), Pérez, Julio (author)Partial nitritation was stably achieved in a bench-scale airlift reactor (1.5L) containing granular sludge. Continuous operation at 20 °C treating low-strength synthetic wastewater (50 mg N-NH<sub>4</sub> <sup>+</sup>/L and no COD) achieved nitrogen loading rates of 0.8 g N-NH<sub>4</sub> <sup>+</sup>/(L·d) during partial nitritation. The...journal article 2016
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Jenie, Y.I. (author), van Kampen, E. (author), de Visser, C.C. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)This paper proposes a novel avoidance method called the three-dimensional velocity obstacle method. The method is designed for unmanned aerial vehicle applications, in particular to autonomously handle uncoordinated multiple encounters in an integrated airspace, by exploiting the limited space in a three-dimensional manner. The method is a three...journal article 2016
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Jenie, Y.I. (author), van Kampen, E. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)This paper proposes a taxonomy of Conflict Detection and Resolution (CD&R) approaches for Unmanned Aerial Vehicles (UAV) operation in an integrated airspace. Possible approaches for UAVs are surveyed and broken down based on their types of surveillance, coordination, maneuver, and autonomy. The factors are combined back selectively, with...journal article 2016
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Pietra, F. (author), Kirkwood, N.R.M. (author), De Trizio, L. (author), Hoekstra, Anne W. (author), Kleibergen, Lennart (author), Renaud, N. (author), Koole, Rolf (author), Baesjou, Patrick J. (author), Manna, L. (author), Houtepen, A.J. (author)In this work, we demonstrate that a preferential Ga-for-Zn cation exchange is responsible for the increase in photoluminescence that is observed when gallium oleate is added to InZnP alloy QDs. By exposing InZnP QDs with varying Zn/In ratios to gallium oleate and monitoring their optical properties, composition, and size, we conclude that Ga3+...journal article 2017
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Sun, Junzi (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)AUTOMATIC dependent surveillance–broadcast (ADS-B) [1,2] is widely implemented in modern commercial aircraft and will become mandatory equipment in 2020. Flight state information such as position, velocity, and vertical rate are broadcast by tens of thousands of aircraft around the world constantly using onboard ADS-B transponders. These data...journal article 2017
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van Driel, B.A. (author), Artesani, A. (author), van den Berg, K.J. (author), Dik, J. (author), Mosca, S. (author), Rossenaar, B. (author), Hoekstra, J. (author), Davies, A. (author), Nevin, A. (author), Valentini, G. (author), Comelli, D. (author)This work reports the analysis of the time-resolved photoluminescence behaviour on the nanosecond and microsecond time scale of fourteen historical and contemporary titanium white pigments. The pigments were produced with different production methods and post-production treatments, giving rise to a remarkable variability of titanium dioxide...journal article 2018
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Sun, Junzi (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)Aircraft mass is a crucial piece of information for studies on aircraft performance, trajectory prediction, and many other topics of aircraft traffic management. However, It is a common challenge for researchers, as well as air traffic control, to access this proprietary information. Previously, several studies have proposed methods to estimate...journal article 2018
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Hoekstra, M. (author), Geilvoet, Stefan P. (author), Hendrickx, Tim L.G. (author), van Erp Taalman Kip, Charlotte S. (author), Kleerebezem, R. (author), van Loosdrecht, Mark C.M. (author)The aim of this research was to study the biological feasibility of the Partial Nitritation/Anammox (PN/A) technology to remove nitrogen from municipal mainstream wastewaters. During stable process operations at summer temperatures (23.2 ± 1.3°C), the total nitrogen removal rate was 0.223 ± 0.029 kg N (m<sup>3 </sup>d)<sup>−1</sup> while at...journal article 2018