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van Lent, P.H. (author), Schmitz, Joep (author), Abeel, T.E.P.M.F. (author)Combinatorial pathway optimization is an important tool in metabolic flux optimization. Simultaneous optimization of a large number of pathway genes often leads to combinatorial explosions. Strain optimization is therefore often performed using iterative design-build-test-learn (DBTL) cycles. The aim of these cycles is to develop a product...journal article 2023