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Winterbach, W. (author), Van Mieghem, P. (author), Reinders, M. (author), Wang, H. (author), De Ridder, D. (author)Molecular interactions are often represented as network models which have become the common language of many areas of biology. Graphs serve as convenient mathematical representations of network models and have themselves become objects of study. Their topology has been intensively researched over the last decade after evidence was found that...journal article 2013
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Trajanovski, S. (author), Martín-Hernández, J. (author), Winterbach, W. (author), Van Mieghem, P. (author)We study the robustness of networks under node removal, considering random node failure, as well as targeted node attacks based on network centrality measures. Whilst both of these have been studied in the literature, existing approaches tend to study random failure in terms of average-case behavior, giving no idea of how badly network...journal article 2013
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- Winterbach, W. (author), De Ridder, D. (author), Wang, H.J. (author), Reinders, M. (author), Van Mieghem, P. (author) conference paper 2012
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- Wang, H. (author), Winterbach, W. (author), Van Mieghem, P.F.A. (author) journal article 2011
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- Winterbach, W. (author), Wang, H. (author), Reinders, M. (author), Van Mieghem, P. (author), De Ridder, D. (author) conference paper 2010
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Winterbach, W. (author), Wang, H. (author), Reinders, M. (author), Van Mieghem, P. (author), De Ridder, D. (author)Biological networks exhibit intriguing topological properties such as small-worldness. In this paper, we investigate whether the topology of a metabolic network is related to its robustness. We do so by perturbing a metabolic system in silico, one reaction at a time and studying the correlations between growth, as predicted by flux balance...conference paper 2010