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Schouten, Philip C. (author), Richters, Lisa (author), Vis, Daniel J. (author), Kommoss, Stefan (author), Kluin, Roelof J.C. (author), Lips, Esther H. (author), Schmidt, Sandra (author), Nederlof, Petra M. (author), Wessels, L.F.A. (author)Purpose: Previously, we developed breast cancer BRCA1-like and BRCA2-like copy-number profile shrunken centroid classifiers predictive for mutation status and response to therapy, targeting homologous recombination deficiency (HRD). Therefore, we investigated BRCA1- and BRCA2-like classification in ovarian cancer, aiming to acquire...journal article 2021
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van Kordelaar, J. (author), van de Ruit, M.L. (author), Solis Escalante, T. (author), Aerden, Leo A.M. (author), Meskers, Carel G.M. (author), van Wegen, Erwin E.H. (author), Schouten, A.C. (author), Kwakkel, Gert (author), van der Helm, F.C.T. (author)Background: Proprioception is important for regaining motor function in the paretic upper extremity after stroke. However, clinical assessments of proprioception are subjective and require verbal responses from the patient to applied proprioceptive stimuli. Cortical responses evoked by robotic wrist perturbations and measured by...journal article 2021
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Piastra, Maria Carla (author), van der Cruijsen, J. (author), Piai, Vitória (author), Jeukens, Floor E.M. (author), Manoochehri, M. (author), Schouten, A.C. (author), Selles, R.W. (author), Oostendorp, Thom (author)Objective. Large structural brain changes, such as chronic stroke lesions, alter the current pathways throughout the patients' head and therefore have to be taken into account when performing transcranial direct current stimulation simulations. Approach. We implement, test and distribute the first MATLAB pipeline that automatically generates...journal article 2021
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van ’t Veld, Ronald C. (author), Schouten, A.C. (author), van der Kooij, H. (author), van Asseldonk, Edwin H.F. (author)Background: People with brain or neural injuries, such as cerebral palsy or spinal cord injury, commonly have joint hyper-resistance. Diagnosis and treatment of joint hyper-resistance is challenging due to a mix of tonic and phasic contributions. The parallel-cascade (PC) system identification technique offers a potential solution to...journal article 2021
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van den Berg, Boudewijn (author), Manoochehri, M. (author), Kasting, Mindy (author), Schouten, A.C. (author), van der Helm, F.C.T. (author), Buitenweg, Jan R. (author)A sustained sensory stimulus with a periodic variation of intensity creates an electrophysiological brain response at associated frequencies, referred to as the steady-state evoked potential (SSEP). The SSEPs elicited by the periodic stimulation of nociceptors in the skin may represent activity of a brain network that is primarily involved in...journal article 2021
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Waasdorp, R. (author), Mugge, W. (author), Vos, H.J. (author), De Groot, Jurriaan H. (author), Verweij, M.D. (author), de Jong, N. (author), Schouten, A.C. (author), Daeichin, V. (author)Skeletal muscles generate force, enabling movement through a series of fast electro-mechanical activations coordinated by the central nervous system. Understanding the underlying mechanism of such fast muscle dynamics is essential in neuromuscular diagnostics, rehabilitation medicine and sports biomechanics. The unique combination of...journal article 2021
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Pompili, M. (author), Hermans, S.L.N. (author), Baier, S. (author), Beukers, H.K.C. (author), Humphreys, P.C. (author), Schouten, R.N. (author), Vermeulen, R.F.L. (author), Tiggelman, M.J. (author), Dos Santos Martins, L. (author), Dirkse, B. (author), Wehner, S.D.C. (author), Hanson, R. (author)The distribution of entangled states across the nodes of a future quantum internet will unlock fundamentally new technologies. Here, we report on the realization of a three-node entanglement-based quantum network. We combine remote quantum nodes based on diamond communication qubits into a scalable phase-stabilized architecture, supplemented...journal article 2021
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Sharifi, S. (author), Luft, F. (author), Potgieter, S. (author), Heida, T. (author), Mugge, W. (author), Schouten, A.C. (author), Bour, L. J. (author), van Rootselaar, A. F. (author)Objective: A role of the motor cortex in tremor generation in essential tremor (ET) is assumed, yet the directionality of corticomuscular coupling is unknown. Our aim is to clarify the role of the motor cortex. To this end we also study ‘familial cortical myoclonic tremor with epilepsy’ (FCMTE) and slow repetitive voluntary movements with a...journal article 2021
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van der Cruijsen, J. (author), Manoochehri, M. (author), Jonker, Z.D. (author), Andrinopoulou, Eleni Rosalina (author), Frens, Maarten A. (author), Ribbers, G.M. (author), Schouten, A.C. (author), Selles, R.W. (author)Neurophysiologic correlates of motor learning that can be monitored during neurorehabilitation interventions can facilitate the development of more effective learning methods. Previous studies have focused on the role of the beta band (14–30 Hz) because of its clear response during motor activity. However, it is difficult to discriminate...journal article 2021
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Yang, Y. (author), Yao, Jun (author), Dewald, Julius (author), van der Helm, F.C.T. (author), Schouten, A.C. (author)This paper introduces the Cross-frequency Amplitude Transfer Function (CATF), a model-free method for quantifying nonlinear stimulus-response interaction based on phase-locked amplitude relationship. The CATF estimates the amplitude transfer from input frequencies at stimulation signal to their harmonics/intermodulation at the response signal....journal article 2020
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Emmanouil, Stergios (author), Aguilar, Sandra Gaytan (author), Nane, G.F. (author), Schouten, Jan Joost (author)Installation and maintenance strategies regarding offshore wind farm operations involve extensive logistics. The main focus is the right temporal and spatial placement of personnel and equipment, while taking into account forecasted meteorological and ocean conditions. For these operations to be successful, weather windows characterized by...journal article 2020
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Luft, Frauke (author), Sharifi, Sarvi (author), Mugge, W. (author), Schouten, A.C. (author), Bour, Lo J. (author), Van Rootselaar, Anne Fleur (author), Veltink, Peter H. (author), Heida, Tijtske (author)Background: Parkinson's disease (PD) and essential tremor (ET) are neurodegenerative diseases characterized by movement deficits. Especially in PD, maintaining cyclic movement can be significantly disturbed due to pathological changes in the basal ganglia and the cerebellum. Providing external cues improves timing of these movements in PD and...journal article 2020
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Schut, I.M. (author), Pasma, J.H. (author), Roelofs, J. M.B. (author), Weerdesteyn, V. (author), van der Kooij, H. (author), Schouten, A.C. (author)Changes in human balance control can objectively be assessed using system identification techniques in combination with support surface translations. However, large, expensive and complex motion platforms are required, which are not suitable for the clinic. A treadmill could be a simple alternative to apply support surface translations. In...journal article 2020
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Paquelet Wuetz, B. (author), Bavdaz, P.L. (author), Yeoh, L.A. (author), Schouten, R.N. (author), van der Does, C.H. (author), Tiggelman, M.J. (author), Sabbagh, D. (author), Sammak, A. (author), Almudever, Carmen G. (author), Sebastiano, F. (author), Clarke, J. S. (author), Veldhorst, M. (author), Scappucci, G. (author)Continuing advancements in quantum information processing have caused a paradigm shift from research mainly focused on testing the reality of quantum mechanics to engineering qubit devices with numbers required for practical quantum computation. One of the major challenges in scaling toward large-scale solid-state systems is the limited input...journal article 2020
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Rahmati, Zahra (author), Behzadipour, Saeed (author), Schouten, A.C. (author), Taghizadeh, Ghorban (author), Firoozbakhsh, Keikhosrow (author)BACKGROUND: Balance training improves postural control in Parkinson's disease (PD). However, a systematic approach for the development of individualized, optimal training programs is still lacking, as the learning dynamics of the postural control in PD, over a training program, are poorly understood. OBJECTIVES: We investigated the learning...journal article 2020
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Dialynas, G. (author), de Haan, Jelle (author), Schouten, A.C. (author), Happee, R. (author), Schwab, A.L. (author)The objective of this study was to identify the dynamic response of the bicycle rider’s body during translational perturbations, in an effort to improve two-wheeler safety and comfort. A bicycle mock-up was equipped with sensors measuring three-dimensional seat and trunk accelerations and rider’s force responses at the seat, handlebars, and...journal article 2020
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Schouten, D.G.M. (author), Massink, Pim (author), Donker, Stella F. (author), Neerincx, M.A. (author)In this study, we attempt to specify the cognitive support behavior of a previously designed embodied conversational agent coach that provides learning support to low-literates. Three knowledge gaps are identified in the existing work: an incomplete specification of the behaviors that make up ‘support,’ an incomplete specification of how this...journal article 2020
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Korver, Sander (author), Schouten, Eva (author), Moultos, O. (author), Vergeer, Peter (author), Grutters, Michiel M.P. (author), Peschier, Leo J.C. (author), Vlugt, T.J.H. (author), Ramdin, M. (author)In arson cases, evidence such as DNA or fingerprints is often destroyed. One of the most important evidence modalities left is relating fire accelerants to a suspect. When gasoline is used as accelerant, the aim is to find a strong indication that a gasoline sample from a fire scene is related to a sample of a suspect. Gasoline samples from a...journal article 2020
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Luft, Frauke (author), Sharifi, Sarvi (author), Mugge, W. (author), Schouten, A.C. (author), Bour, Lo J. (author), Van Rootselaar, Anne Fleur (author), Veltink, Peter H. (author), Heida, Tijtske (author)Background: The basal ganglia and cerebellum are brain structures involved in movement initiation, execution and termination. They are thought to be involved in the tremor generation and movement deficits in Parkinson's disease (PD) and essential tremor (ET). Especially in PD, maintaining cyclic movement, such as walking or tapping can be...journal article 2019
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Bouts, Mark J.R.J. (author), van der Grond, Jeroen (author), Vernooij, Meike W. (author), Koini, Marisa (author), Schouten, T.M. (author), de Vos, Frank (author), Feis, Rogier A. (author), Lechner, Anita (author), Niessen, W.J. (author)Early and accurate mild cognitive impairment (MCI) detection within a heterogeneous, nonclinical population is needed to improve care for persons at risk of developing dementia. Magnetic resonance imaging (MRI)-based classification may aid early diagnosis of MCI, but has only been applied within clinical cohorts. We aimed to determine the...journal article 2019