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Difrancesco, S. (author), van Baardewijk, J.U. (author), Cornelissen, A.S. (author), Varon, Carolina (author), Hendriks, R.C. (author), Bouwer, A.M. (author)Wearable sensors offer new opportunities for the early detection and identification of toxic chemicals in situations where medical evaluation is not immediately possible. We previously found that continuously recorded physiology in guinea pigs can be used for early detection of exposure to an opioid (fentanyl) or a nerve agent (VX), as well as...journal article 2023
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Toward complete oral cavity cancer resection using a handheld diffuse reflectance spectroscopy probeBrouwer de Koning, Susan G. (author), Baltussen, Elisabeth J.M. (author), Karakullukcu, M. Baris (author), Dashtbozorg, Behdad (author), Smit, Laura A. (author), Dirven, Richard (author), Hendriks, B.H.W. (author), Sterenborg, Henricus J.C.M. (author), Ruers, Theo J.M. (author)This ex-vivo study evaluates the feasibility of diffuse reflectance spectroscopy (DRS) for discriminating tumor from healthy tissue, with the aim to develop a technology that can assess resection margins for the presence of tumor cells during oral cavity cancer surgery. Diffuse reflectance spectra were acquired on fresh surgical specimens...journal article 2018
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Baltussen, Elisabeth J.M. (author), Snaebjornsson, Petur (author), De Koning, Susan G.Brouwer (author), Sterenborg, Henricus J.C.M. (author), Aalbers, Arend G.J. (author), Kok, Niels (author), Beets, Geerard L. (author), Hendriks, B.H.W. (author), Kuhlmann, Koert F.D. (author), Ruers, Theo J.M. (author)Colorectal surgery is the standard treatment for patients with colorectal cancer. To overcome two of the main challenges, the circumferential resection margin and postoperative complications, real-time tissue assessment could be of great benefit during surgery. In this ex vivo study, diffuse reflectance spectroscopy (DRS) was used to...journal article 2017