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Berenger-Currias, N.M.L.P. (author), Mircea, Maria (author), Adegeest, Esmée (author), van den Berg, Patrick R. (author), Feliksik, Marleen (author), Hochane, Mazène (author), Idema, T. (author), Tans, S.J. (author), Semrau, Stefan (author)Stem-cell derived in vitro systems, such as organoids or embryoids, hold great potential for modeling in vivo development. Full control over their initial composition, scalability, and easily measurable dynamics make those systems useful for studying specific developmental processes in isolation. Here we report the formation of gastruloids...journal article 2022
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van der Voorn, Tom (author), van den Berg, Caroline (author), Quist, J.N. (author), Kok, Kasper (author)The current COVID-19 pandemic has affected societies across the world while its economic impact has cut deeper than any recession since the Second World War. Climate change is potentially an even more disruptive and complex global challenge. Climate change could cause social and economic damage far larger than that caused by COVID-19. The...journal article 2022
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Kwakernaak, M.C. (author), Koel, Marijn (author), van den Berg, P.M. (author), Kelder, E.M. (author), Jager, W.F. (author)A novel protocol for the synthesis of perylene diimides (PDIs), by reacting perylene dianhydride (PDA) with aliphatic amines is reported. Full conversions were obtained at temperatures between 20 and 60 °C, using DBU as the base in DMF or DMSO. A "green"synthesis of PDIs, that runs at higher temperatures, was developed using K2CO3 in DMSO....journal article 2022
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Wang, Gangqi (author), Heijs, Bram (author), Kostidis, Sarantos (author), Rietjens, Rosalie G.J. (author), Mahfouz, A.M.E.T.A. (author), Chuva de Sousa Lopes, Susana M. (author), van den Berg, Cathelijne W. (author), van den Berg, Bernard M. (author), Rabelink, Ton J. (author)Accumulating evidence demonstrates important roles for metabolism in cell fate determination. However, it is a challenge to assess metabolism at a spatial resolution that acknowledges both heterogeneity and cellular dynamics in its tissue microenvironment. Using a multi-omics platform to study cell-type-specific dynamics in metabolism in...journal article 2022
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Wang, Gangqi (author), Heijs, Bram (author), Kostidis, Sarantos (author), Mahfouz, A.M.E.T.A. (author), Rietjens, Rosalie G.J. (author), Bijkerk, Roel (author), Koudijs, Angela (author), van der Pluijm, Loïs A.K. (author), van den Berg, Cathelijne W. (author)A common drawback of metabolic analyses of complex biological samples is the inability to consider cell-to-cell heterogeneity in the context of an organ or tissue. To overcome this limitation, we present an advanced high-spatial-resolution metabolomics approach using matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI...journal article 2022
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Dekker, W.J.C. (author), Jürgens, H. (author), Ortiz Merino, R.A. (author), Mooiman, C. (author), van den Berg, Remon (author), Kaljouw, Astrid (author), Mans, R. (author), Pronk, J.T. (author)While thermotolerance is an attractive trait for yeasts used in industrial ethanol production, oxygen requirements of known thermotolerant species are incompatible with process requirements. Analysis of oxygen-sufficient and oxygen-limited chemostat cultures of the facultatively fermentative, thermotolerant species Ogataea parapolymorpha...journal article 2022
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van den Berg, Tomas E. (author), Dutta, S. (author), Kaiser, Elias (author), Vialet-Chabrand, Silvere (author), van der Ploeg, Martine (author), van Emmerik, Tim (author), Coenders-Gerrits, Miriam (author), ten Veldhuis, Marie-claire (author)Plant transpiration accounts for about half of all terrestrial evaporation. Plants need water for many vital functions including nutrient uptake, growth and leaf cooling. The regulation of plant water transport by stomata in the leaves leads to the loss of 97% of the water that is taken up via their roots, to the atmosphere. Measuring plant...book chapter 2022
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van den Berg, S.C. (author), Scharff, R.B.N. (author), Rusak, Z. (author), Wu, J. (author)We present OpenFish: an open source soft robotic fish which is optimized for speed and efficiency. The soft robotic fish uses a combination of an active and passive tail segment to accurately mimic the thunniform swimming mode. Through the implementation of a novel propulsion system that is capable of achieving higher oscillation frequencies...journal article 2022
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Hendrikse, H. (author), Hammer, T.C. (author), van den Berg, M.A. (author), Willems, Tom (author), Owen, C.C. (author), van Beek, C. (author), Ebben, Nick J.J. (author), Puolakka, Otto (author), Polojärvi, Arttu (author)Basin tests were performed at the Aalto Ice Tank to gather data on ice-structure action and interaction from ice failing against a vertically sided cylindrical pile. The tests were performed with a real-time hybrid test setup, which combined physical and numerical components to simulate a range of test structures in real-time. The dataset...journal article 2022
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- van den Berg, Marc (author), Schraven, D.F.J. (author), Schultheiss, F.G. (author), Frese, Tristan (author) conference paper 2022
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van den Berg, T.G.C. (author), Kroesen, M. (author), Chorus, C.G. (author)Within moral psychology, theories focusing on the conceptualization and empirical measurement of people’s morality in terms of general moral values –such as Moral Foundation Theory- (implicitly) assume general moral values to be relevant concepts for the explanation and prediction of behavior in everyday life. However, a solid theoretical and...journal article 2022
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van den Berg, L. (author), Toja Ortega, S. (author), van Loosdrecht, Mark C.M. (author), de Kreuk, M.K. (author)Aerobic granular sludge (AGS) is an advanced biofilm-based technology for wastewater treatment. Diffusion of substrates into the granules is a key aspect of this technology. Domestic wastewater contains soluble organic substrates of different sizes that could potentially diffuse into the granules. In this study, the relation between the...journal article 2022
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Hammer, T.C. (author), Owen, C.C. (author), van den Berg, M.A. (author), Hendrikse, H. (author)Ice-induced vibrations of offshore wind turbines on monopile foundations were investigated experimentally at the Aalto Ice Tank. A real-time hybrid test setup was developed allowing to accurately simulate the motion of a wind turbine in interaction with ice, incorporating the multi-modal aspects of the interaction and the effect of simultaneous...conference paper 2022
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Vardon, P.J. (author), Laumann, S.J. (author), Schmiedel, T. (author), Vargas Meleza, L. (author), Barnhoorn, A. (author), Abels, H.A. (author), Drijkoningen, G.G. (author), Dieudonné, A.A.M. (author), Beernink, S.T.W. (author), van den Berg, J.J. (author)The multi-purpose research borehole at the Delftse Hout is the third of four seismic monitoring locations of the seismic monitoring network for the geothermal research project on the TU Delft campus (Geothermal Delft GTD, also known as DAPwell, https://geothermiedelft.nl/). For the geothermal research project, two deep wells (“a doublet”...report 2022
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Bruggeman, A.M.R.M. (author), van Manen, H.S. (author), van der Laan, Ton (author), van den Berg, Tobie (author), la Rocca, G. (author)According to a study performed by the Project Management Institute, around 47% of unsuccessful projects do not meet their goals and objectives due to poor requirements management. Taking requirements into account during the aircraft design process and ensuring requirement compliance during all design phases is important to obtain good and...conference paper 2022
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van den Berg, L. (author), Pronk, M. (author), van Loosdrecht, Mark C.M. (author), de Kreuk, M.K. (author)Granular sludge processes are frequently used in domestic and industrial wastewater treatment. The granule buoyant density and biomass density are important parameters for the design and operation of granular sludge reactors. Different methods to measure the granule density include the pycnometer method, the Percoll density gradient method,...journal article 2022
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van den Berg, Boudewijn (author), Manoochehri, M. (author), Schouten, A.C. (author), van der Helm, F.C.T. (author), Buitenweg, Jan R. (author)Recent studies have established the presence of nociceptive steady-state evoked potentials (SSEPs), generated in response to thermal or intra-epidermal electric stimuli. This study explores cortical sources and generation mechanisms of nociceptive SSEPs in response to intra-epidermal electric stimuli. Our method was to stimulate healthy...journal article 2022
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Hendrikse, H. (author), Hammer, T.C. (author), Owen, C.C. (author), van den Berg, M.A. (author), van Beek, C. (author), Polojärvi, Arttu (author), Puolakka, Otto (author), Willems, Tom (author)With the recent surge in development of offshore wind in the Baltic Sea, Bohai Sea and other ice-prone regions, a need has arisen for new basin tests to qualify the interaction between offshore wind turbines and sea ice. To this end, a series of model tests was performed at the Aalto ice basin as part of the SHIVER project. The tests were aimed...conference paper 2022
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Vermeer, C.M. (author), Depaz, Lena (author), van den Berg, Emily (author), Koelmans, Tom (author), Kleerebezem, R. (author)Medium-chain-length polyhydroxyalkanoate (mcl-PHA) production by using microbial enrichments is a promising but largely unexplored approach to obtain elastomeric biomaterials from secondary resources. In this study, several enrichment strategies were tested to select a community with a high mcl-PHA storage capacity when feeding octanoate. On...journal article 2022
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van den Berg, D. (author), De Tavernier, D. (author), van Wingerden, J.W. (author)In recent years dynamic induction control has shown great potential in reducing wake-to-turbine interaction by increasing the mixing in the wake. With these wake mixing methods the thrust force will vary in time. If applied to a floating offshore wind turbine, it will cause the platform to move. In this paper the effect of the Helix mixing...journal article 2022