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Sharman, Kavya (author), Patterson, Nathan Heath (author), Weiss, Andy (author), Neumann, Elizabeth K. (author), Guiberson, Emma R. (author), Ryan, Daniel J. (author), Gutierrez, Danielle B. (author), Spraggins, Jeffrey M. (author), Van de Plas, Raf (author), Skaar, Eric P. (author), Caprioli, Richard M. (author)
Spatially targeted proteomics analyzes the proteome of specific cell types and functional regions within tissue. While spatial context is often essential to understanding biological processes, interpreting sub-region-specific protein profiles can pose a challenge due to the high-dimensional nature of the data. Here, we develop a multivariate...
journal article 2023
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Reyes, Nicolás (author), Mayorga, Ivan Cámara (author), Grutzeck, Gerrit (author), Yates, Stephen J.C. (author), Baryshev, Andrey (author), Baselmans, J.J.A. (author), Weiss, Axel (author), Klein, Bernd (author)
Characterization of wide-field optics in the Terahertz regime imposes new and demanding requirements for testing systems. Basic optical parameters can be determined from scalar planar characterization, obtained using monochromatic or thermal sources located in the instrument focal plane. In contrast, important features, such as the spillover...
journal article 2023
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Maurits, Marc P. (author), Korsunsky, Ilya (author), Raychaudhuri, Soumya (author), Murphy, Shawn N. (author), Smoller, Jordan W. (author), Weiss, Scott T. (author), Huizinga, Thomas W.J. (author), Reinders, M.J.T. (author), van den Akker, E.B. (author)
Objective: To facilitate patient disease subset and risk factor identification by constructing a pipeline which is generalizable, provides easily interpretable results, and allows replication by overcoming electronic health records (EHRs) batch effects. Material and Methods: We used 1872 billing codes in EHRs of 102 880 patients from 12...
journal article 2022
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Rivera, Emilio S. (author), Weiss, Andy (author), Migas, L.G. (author), Freiberg, Jeffrey A. (author), Djambazova, Katerina V. (author), Neumann, Elizabeth K. (author), Van de Plas, Raf (author), Spraggins, Jeffrey M. (author), Skaar, Eric P. (author), Caprioli, Richard M. (author)
Introduction: Although Staphylococcus aureus is the leading cause of biofilm-related infections, the lipidomic distributions within these biofilms is poorly understood. Here, lipidomic mapping of S. aureus biofilm cross-sections was performed to investigate heterogeneity between horizontal biofilm layers. Methods: S. aureus biofilms were...
journal article 2022
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Jansen, K.M.B. (author), Zhang, M. F. (author), Ernst, L. J. (author), Vu, D. K. (author), Weiss, L. (author)
In this paper we propose a new multistep characterisation method to be able to map out the dependency of moisture diffusion parameters of a polymeric material over a range of temperature and humidity conditions in a limited amount of time. We do that by (1) using a moisture sorption analyser which can continuously monitor weight changes with...
journal article 2020
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Tolmeijer, Suzanne (author), Weiss, Astrid (author), Hanheide, Marc (author), Lindner, Felix (author), Powers, Thomas M. (author), Dixon, Clare (author), Tielman, M.L. (author)
We develop a taxonomy that categorizes HRI failure types and their impact on trust to structure the broad range of knowledge contributions. We further identify research gaps in order to support fellow researchers in the development of trustworthy robots. Studying trust repair in HRI has only recently been given more interest and we propose a...
conference paper 2020
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Yik, Hiufai (author), Valori, V. (author), Weiss, Stephan (author)
We report on Rayleigh-Bénard convection with strongly varying fluid properties experimentally and theoretically. Using pressurized sulfur-hexafluoride (SF6) above its critical point, we are able to make measurements at mean temperatures (Tm) and pressures (Pm) along Prandtl-number isolines in the (T,P) parameter space. This allows us to keep...
journal article 2020
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Agarwal, Girish (author), Allen, Roland E. (author), Bezděková, Iva (author), Boyd, Robert W. (author), Chen, Goong (author), Hanson, R. (author), Hawthorne, Dean L. (author), Hemmer, Philip (author), Kim, Moochan B. (author), Kocharovskaya, Olga (author), Lee, D. (author), Lidström, Sebastian K. (author), Lidström, Suzy (author), Losert, Harald (author), Maier, Helmut (author), Neuberger, John W. (author), Padgett, Miles J. (author), Raizen, Mark (author), Rajendran, Surjeet (author), Rasel, Ernst (author), Schleich, Wolfgang P. (author), Scully, Marlan O. (author), Shchedrin, Gavriil (author), Shvets, Gennady (author), Sokolov, Alexei (author), Svidzinsky, Anatoly (author), Walsworth, Ronald L. (author), Weiss, Rainer (author), Wilczek, Frank (author), Willner, Alan E. (author), Yablonovich, Eli (author), Zheludev, Nikolay (author)
The Winter Colloquium on the Physics of Quantum Electronics (PQE) has been a seminal force in quantum optics and related areas since 1971. It is rather mind-boggling to recognize how the concepts presented at these conferences have transformed scientific understanding and human society. In January 2017, the participants of PQE were asked to...
journal article 2018
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van Gent, P.L. (author), Michaelis, D (author), van Oudheusden, B.W. (author), Weiss, P.E. (author), de Kat, R. (author), Laskari, A. (author), Jeon, Y.J. (author), David, L (author), Schanz, D (author), Huhn, F. (author), Gesemann, S (author), Novara, M. (author), McPhaden, C. (author), Neeteson, N. J. (author), Rival, David E. (author), Schneiders, J.F.G. (author), Schrijer, F.F.J. (author)
A test case for pressure field reconstruction from particle image velocimetry (PIV) and Lagrangian particle tracking (LPT) has been developed by constructing a simulated experiment from a zonal detached eddy simulation for an axisymmetric base flow at Mach 0.7. The test case comprises sequences of four subsequent particle images (representing...
journal article 2017
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van Beek, Daphne M (author), Straver, R. (author), Weiss, Marian M. (author), Boon, Elles M.J. (author), Huijsdens-van Amsterdam, Karin (author), Oudejans, Cees B.M. (author), Reinders, M.J.T. (author), Sistermans, Erik A. (author)
Objective: To compare available analysis methods for determining fetal fraction on single read next generation sequencing data. This is important as the performance of non-invasive prenatal testing (NIPT) procedures depends on the fraction of fetal DNA. Methods: We tested six different methods for the detection of fetal fraction in NIPT...
journal article 2017
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Straver, R. (author), Weiss, Marjan M. (author), Waisfisz, Quinten (author), Sistermans, Erik A. (author), Reinders, M.J.T. (author)
In clinical genetics, detection of single nucleotide polymorphisms (SNVs) as well as copy number variations (CNVs) is essential for patient genotyping. Obtaining both CNV and SNV information from WES data would significantly simplify clinical workflow. Unfortunately, the sequence reads obtained with WES vary between samples, complicating...
journal article 2017
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Holstege, H. (author), van der Lee, S.J. (author), Hulsman, M. (author), Hang Wong, Tsz (author), van Rooij, Jeroen G.J. (author), Weiss, Marjan (author), Louwersheimer, Eva (author), Wolters, Frank J, (author), Amin, Najaf (author), Reinders, M.J.T. (author)
Accumulating evidence suggests that genetic variants in the SORL1 gene are associated with Alzheimer disease (AD), but a strategy to identify which variants are pathogenic is lacking. In a discovery sample of 115 SORL1 variants detected in 1908 Dutch AD cases and controls, we identified the variant characteristics associated with SORL1...
journal article 2017
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van Beek, Daphne M (author), Straver, R. (author), Weiss, Marian M. (author), Boon, Elles M.J. (author), Huijsdens-van Amsterdam, Karin (author), Oudejans, Cees B.M. (author), Reinders, M.J.T. (author), Sistermans, Erik A. (author)
No abstract is available for this article.<br/>
journal article 2017
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Blinde, P (author), Michaelis, D (author), van Oudheusden, B.W. (author), Weiss, P.E. (author), de Kat, R. (author), Laskari, A. (author), Jeon, Y.J. (author), David, L (author), Schanz, D (author), Huhn, F. (author), Gesemann, S (author), Novara, M. (author), McPhaden, C. (author), Neeteson, N. (author), Rival, D. (author), Schneiders, J.F.G. (author), Schrijer, F.F.J. (author)
A test case for PIV-based pressure evaluation techniques has been developed by constructing a simulated experiment from a ZDES simulation for an axisymmetric base flow at Mach 0.7. The test case comprises sequences of four subsequent particle images (representing multi-pulse data) as well as continuous time-resolved data. Particle images were...
conference paper 2016
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Sharp transitions between potentially different turbulent states are unexpected because one might think that they should be washed out by the prevailing intense fluctuations and short coherence lengths and times. Contrary to this expectation, we found a sequence of such transitions in turbulent rotating Rayleigh-Bénard convection as the rotation...
conference paper 2015
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Yurtsever, G. (author), Weiss, N. (author), Kalkman, J. (author), Van Leeuwen, T.G. (author), Baets, R. (author)
We demonstrate an ultra-compact silicon integrated photonic interferometer for swept-source optical coherence tomography (SS-OCT). The footprint of the integrated interferometer is only 0.75×5??mm2. The design consists of three 2×2 splitters, a 13 cm physical length (50.4 cm optical length) reference arm, and grating couplers. The photonic...
journal article 2014
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Ranjbar-Sahraei, B. (author), Alers, S. (author), Stankova, K. (author), Tuyls, K. (author), Weiss, G. (author)
Diversity and inequality are essences of our real world. Ant colonies are comprised of hundreds of individuals, with no two of them being exactly identical. A flock of birds contains individuals with slight variations in size, speed and vision. Looking at human societies such diversity can be seen among individuals differing in body shape and in...
conference paper 2013
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Bou Ammar, H. (author), Mocanu, D.C. (author), Taylor, M.E. (author), Driessens, K. (author), Weiss, G. (author), Tuyls, K. (author)
conference paper 2013
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Chen, S. (author), Ammar, H.B. (author), Tuyls, K. (author), Weiss, G. (author)
This paper deals with a prominent type of complex negotiations. We propose a novel negotiation strategy called Dragon which employs sparse pseudo-input Gaussian processes (SPGPs) to model efficiently the behavior of the negotiating opponents. The experimental results provided in this paper show that Dragon outperforms the state-of-the-art...
conference paper 2013
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Weiss, N. (author), Van Leeuwen, T.G. (author), Kalkman, J. (author)
We report on localized measurement of the longitudinal and transverse flow velocities in a colloidal suspension using optical coherence tomography. We present a model for the path-length resolved autocorrelation function including diffusion and flow, which we experimentally verify. For flow that is not perpendicular to the incident beam, the...
journal article 2013
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