Precision Engineering of the Co-immobilization of Enzymes for Cascade Biocatalysis

The design and orderly layered co-immobilization of multiple enzymes on resin particles remain challenging. In this study, the SpyTag/SpyCatcher binding pair was fused to the N-terminus of an alcohol dehydrogenase (ADH) and an aldo-keto reductase (AKR), respectively. A non-canonical amino acid (ncAA), p-azido-L-phenylalanine (p-AzF), as the...

Rapid extraction of pavement aggregate gradation based on point clouds using deep learning networks

Usage of asphalt mixture with poor gradation will most likely lead to pavement deficiency. There is a growing need for rapid and non-destructive methods to extract pavement aggregate gradation. In this study, a deep learning-based method that utilizes point clouds data for gradation extraction was proposed. Firstly, a data enhancement...

Towards weathering and corrosion resistant, self-warning and self-healing epoxy coatings with tannic acid loaded nanocontainers

In this work, an active protective epoxy coating with weathering resistant, corrosion-warning, and self-healing properties was developed by incorporating tannic acid (TA) loaded mesoporous silica (MSN-TA) nanocontainers. The introduction of MSN-TA nanocontainers could alleviate the coating degradation via scavenging the radicals generated...

Microwave roasting of blast furnace slag for carbon dioxide mineralization and energy analysis

For both the waste treatment of large quantities of blast furnace (BF) slag and carbon dioxide (CO₂) that are discharged in ironworks, mineral carbonation by BF slag was proposed in this decade. However, it has not been widely used due to its high energy consumption and low production efficiency. In this study, a microwave roasting...

"on Water" Direct Organocatalytic Cyanoarylmethylation of Isatins for the Diastereoselective Synthesis of 3-Hydroxy-3-cyanomethyl Oxindoles

An "on water" organocatalytic cyanoarylmethylation of aryl acetonitrile to isatins is developed, giving products in high yields and up to excellent diastereoselectivities. A remarkable enhancement of reaction rates and diastereoselectivities by water was observed under mild conditions. Moreover, this approach provides a highly efficient and...