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Oosterhoff, J.H.F. (author), Dijkstra, H.F. (author), Karhade, Aditya V. (author), Poolman, Rudolf W. (author), Schipper, Inger B. (author), Nelissen, R.G.H.H. (author), van Embden, Daphne (author), Jaarsma, Ruurd L. (author), Schwab, Joseph H. (author)Purpose: Effects of clockwise torque rotation onto proximal femoral fracture fixation have been subject of ongoing debate: fixated right-sided trochanteric fractures seem more rotationally stable than left-sided fractures in the biomechanical setting, but this theoretical advantage has not been demonstrated in the clinical setting to date. The...journal article 2023
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Ooft, Salo N. (author), Weeber, Fleur (author), Dijkstra, Krijn K. (author), McLean, Chelsea M. (author), Kaing, Sovann (author), van Werkhoven, Erik (author), Schipper, Luuk (author), Hoes, Louisa (author), Wessels, L.F.A. (author)There is a clear and unmet clinical need for biomarkers to predict responsiveness to chemotherapy for cancer. We developed an in vitro test based on patient-derived tumor organoids (PDOs) from metastatic lesions to identify nonresponders to standard-of-care chemotherapy in colorectal cancer (CRC). In a prospective clinical study, we show the...journal article 2019