Towards preparative peroxygenase-catalyzed oxyfunctionalization reactions in organic media

The peroxygenase from Agrocybe aegerita (AaeUPO) has been evaluated for stereoselective oxyfunctionalization chemistry under non-aqueous reaction conditions. The stereoselective hydroxylation of ethylbenzene to (R)-1-phenylethanol was performed in neat substrate as reaction medium together with the immobilized biocatalyst and <sup>tert</sup...

Specific oxyfunctionalisations catalysed by peroxygenases: Opportunities, challenges and solutions

Peroxygenases enable H2O2-driven oxyfunctionalisation of organic compounds such as selective epoxidation, hydroxylation and heteroatom oxygenation. Therefore, peroxygenases are potentially very useful tools for the organic chemist. This contribution reviews the current state of the art in peroxygenases, their availability, engineering and...