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Zheng, Dongxu (author), Wondergem, Annelot (author), Kloet, Susan (author), Willemsen, Iris (author), Balog, Judit (author), Tapscott, Stephen J. (author), Mahfouz, A.M.E.T.A. (author), Van Den Heuvel, Anita (author), Van Der Maarel, Silvère M. (author)The sporadic nature of DUX4 expression in FSHD muscle challenges comparative transcriptome analyses between FSHD and control samples. A variety of DUX4 and FSHD-associated transcriptional changes have been identified, but bulk RNA-seq strategies prohibit comprehensive analysis of their spatiotemporal relation, interdependence and role in the...journal article 2024
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van Zadelhoff, Arjan C. (author), Poppe, Jarinda A. (author), Willemsen, Sten (author), Mauff, Katya (author), van Weteringen, Willem (author), Goos, T.G. (author), Reiss, Irwin K.M. (author), Vermeulen, Marijn J. (author), de Graaff, Jurgen C. (author)Background: Arterial pressure measurements are important to monitor vital function in neonates, and values are known to be dependent of gestational and postnatal age. Current reference ranges for mean arterial pressure in neonates have been derived from small samples and combined data of noninvasive and invasive measurements. We aimed to...journal article 2023
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Willemsen, Marguérite (author)Dredging is performed for various reasons, including port development, coastal defense and land reclamation. The economic and social importance of such projects is widely acknowledged, but there are growing concerns about the possible environmental impact of the dredge plumes that form as a temporary by-product of these activities. Suspended...master thesis 2022
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Willemsen, Marloes (author)The Dutch have complicated relationship with nature, since the land is in a constant battle against flooding. Being successful at conquering nature also showed in the increased urbanisation and management of remaining landscape. Due to globalisation, the impact of daily activities on nature remain distant. The world now has entered a so-called ...master thesis 2022
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Willemsen, Koen (author), Niemeyer, Menco J.S. (author), Harlianto, Netanja I. (author), Sadiqi, Said (author), Seevinck, Peter R. (author), Sakkers, Ralph J.B. (author), Weinans, Harrie (author), Van der Wal, Bart C.H. (author)BACKGROUND AND PURPOSE: The Chiari osteotomy was a regular treatment for developmental hip dysplasia before it became mostly reserved as a salvage therapy. However, the long-term survival of the Chiari osteotomy has not been systematically investigated. We investigated the survival time of the Chiari osteotomy until conversion to total hip...journal article 2022
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Willemsen, Koen (author), Tryfonidou, Marianna A. (author), Sakkers, Ralph J.B. (author), Castelein, René M. (author), Beukers, Martijn (author), Seevinck, Peter R. (author), Weinans, Harrie (author), van der Wal, Bart C.H. (author), Meij, Björn P. (author)The concept of a novel patient-specific 3D-printed shelf implant should be evaluated in a relevant large animal model with hip dysplasia. Therefore, three dogs with radiographic bilateral hip dysplasia and a positive subluxation test underwent unilateral acetabular augmentation with a 3D-printed dog-specific titanium implant. The...journal article 2022
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Willemsen, P. W.J.M. (author), Smits, B. P. (author), Borsje, B. W. (author), Herman, P.M.J. (author), Dijkstra, J. T. (author), Bouma, T. J. (author), Hulscher, S. J.M.H. (author)Salt marshes can contribute to coastal protection, but the magnitude of the protection depends on the width of the marsh. The cross-shore width of the marsh is to a large extent determined by the delicate balance between seaward expansion and landward retreat. The influence of the magnitude of daily occurring mild weather conditions and...journal article 2022
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Willemsen, Koen (author), Magré, Joëll (author), Mol, Jeroen (author), Noordmans, Herke Jan (author), Weinans, Harrie (author), Hekman, Edsko E.G. (author), Kruyt, Moyo C. (author)For decades, the advantages of rapid prototyping for clinical use have been recognized. However, demonstrations of potential solutions to treat spinal problems that cannot be solved otherwise are scarce. In this paper, we describe the development, regulatory process, and clinical application of two types of patient specific 3D-printed devices...journal article 2022
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Willemsen, Koen (author), Tryfonidou, Marianna (author), Sakkers, Ralph (author), Castelein, René M. (author), Zadpoor, A.A. (author), Seevinck, Peter (author), Weinans, Harrie (author), Meij, Björn (author), van der Wal, Bart C.H. (author)A solution for challenging hip dysplasia surgery could be a patient-specific 3D-printed shelf implant that is positioned extra-articular and restores the dysplastic acetabular rim to normal anatomical dimensions. The anatomical correction and biomechanical stability of this concept were tested in a canine model that, like humans, also suffers...journal article 2022
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Gijsman, R. (author), Horstman, E.M. (author), Willemsen, P.W.J.M. (author), Swales, A. (author), Wijnberg, K.M. (author)Mangrove seedling establishment is crucial to the long-term development of mangrove forests. This study incorporates a process-based approach for seedling establishment in a process-based hydrodynamic model. The biophysical model is used to simulate seedling establishment in the Firth of Thames estuary (New Zealand). The results are compared to...conference paper 2021
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Willemsen, Daniël (author)Multi-agent robotic systems could benefit from reinforcement learning algorithms that are able to learn behaviours in a small number trials, a property known as sample efficiency. This research investigates the use of learned world models to create more sample-efficient algorithms. We present a novel multi-agent model-based reinforcement...master thesis 2021
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Willemsen, K. (author), Möring, Michelle M. (author), Harlianto, Netanja I. (author), Tryfonidou, Marianna A. (author), van der Wal, Bart C.H. (author), Weinans, Harrie (author), Meij, Björn P. (author), Sakkers, Ralph J. B. (author)Hip dysplasia (HD) is common in both humans and dogs. This interconnection is because humans and dogs descended from a common ancestor and therefore have a similar anatomy at micro- and macroscopic levels. Furthermore, dogs are the animals of choice for testing new treatments for human hip dysplasia and orthopedic surgery in general. However,...review 2021
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Golafshan, Nasim (author), Willemsen, K. (author), Kadumudi, Firoz Babu (author), Vorndran, Elke (author), Dolatshahi-Pirouz, Alireza (author), Weinans, Harrie (author), van der Wal, Bart C.H. (author), Malda, Jos (author), Castilho, Miguel (author)Osteoarthritis of the hip is a painful and debilitating condition commonly occurring in humans and dogs. One of the main causes that leads to hip osteoarthritis is hip dysplasia. Although the current surgical methods to correct dysplasia work satisfactorily in many circumstances, these are associated with serious complications, tissue...journal article 2021
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Kolken, H.M.A. (author), de Jonge, C.P. (author), van der Sloten, T. (author), Garcia, A. Fontecha (author), Pouran, B. (author), Willemsen, K. (author), Weinans, Harrie (author), Zadpoor, A.A. (author)The unprecedented properties of meta-biomaterials could pave the way for the development of life-lasting orthopedic implants. Here, we used non-auxetic meta-biomaterials to address the shortcomings of the current treatment options in acetabular revision surgery. Due to the severe bone deficiencies and poor bone quality, it can be very...journal article 2021
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Hu, Zhan (author), Willemsen, Pim W.J.M. (author), Borsje, Bas W. (author), Wang, Chen (author), Wang, Heng (author), Van Der Wal, Daphne (author), Zhu, Zhenchang (author), Vuik, V. (author), Bouma, Tjeerd J. (author)Tidal flats provide valuable ecosystem services such as flood protection and carbon sequestration. Erosion and accretion processes govern the ecogeomorphic evolution of intertidal ecosystems (marshes and bare flats) and, hence, substantially affect their valuable ecosystem services. To understand the intertidal ecosystem development, high...journal article 2021
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Willemsen, Roger (author)Wingtip-mounted propellers have the ability to enhance the propeller-wing system performance. For inboard-up rotating tractor propellers, the swirl in the propeller slipstream can be used on the wing to reduce the influence of the wingtip vortex, decreasing drag. Furthermore, lift is enhanced by increasing dynamic pressure and angle of attack...master thesis 2020
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Willemsen, Mark (author)Introduction: Smart Medics Company is a startup from the Delft University of Technology, looking to bring an affordable Video laryngoscope (VL) into hospitals in low-resource regions. This research aims to seek the best suitable transparent material to act as a lens, sealing off a compartment containing an endoscope, as well as, bring forth a...master thesis 2020
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Willemsen, Robert (author)The work processes of structural engineers have been changing over the last decades. Digitalisation and automation play an important role in this change. One of the major developments in this context has been the introduction of Building Information Modelling (BIM). In a BIM model the geometry of the actual building is represented. To this...master thesis 2020
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Willemsen, Maurice (author)We consider a system of IoT nodes powered completely by energy harvesting.This work focuses on achieving the time correlation of data measurements ina network of energy harvesting sensor nodes. Time correlation is achieved byhopping a message through the whole network. This message wakes up all thenodes and lets them perform a measurement....master thesis 2020
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Willemsen, K. (author), Doelman, Christiaan J. (author), Sam, Ali S.Y. (author), Seevinck, Peter R. (author), Sakkers, Ralph J.B. (author), Weinans, Harrie (author), van Der Wal, Bart C.H. (author)Background and purpose — The shelf arthroplasty was the regular treatment for residual hip dysplasia before it was substituted by the peri-acetabular osteotomy. Yet, evidence regarding the survival of shelf arthroplasty surgery has never been systematically documented. Hence, we investigated the survival time of the shelf procedure until...journal article 2020