Lysolipids are prominent in subretinal drusenoid deposits, a high-risk phenotype in age-related macular degeneration

Introduction: Age related macular degeneration (AMD) causes legal blindness worldwide, with few therapeutic targets in early disease and no treatments for 80% of cases. Extracellular deposits, including drusen and subretinal drusenoid deposits (SDD; also called reticular pseudodrusen), disrupt cone and rod photoreceptor functions and strongly...

Estimation of drone intention using trajectory frequency defined in radar's measurement phase planes

This paper presents a radar-based algorithm for autonomous estimation of drone intention. The algorithm is based on radar's kinematic measurements, providing fast and robust intention estimation for multiple targets. The core idea of the proposed algorithm is to build intention-specific features for each intention in advance and use them in...

A special issue on Rotorcraft Safety

Protocol for multimodal analysis of human kidney tissue by imaging mass spectrometry and CODEX multiplexed immunofluorescence

Here, we describe the preservation and preparation of human kidney tissue for interrogation by histopathology, imaging mass spectrometry, and multiplexed immunofluorescence. Custom image registration and integration techniques are used to create cellular and molecular atlases of this organ system. Through careful optimization, we ensure high...

Parametric Investigation on Simulated Staring FMCW Radar for Anti-Drone Swarms

This paper presents parametric investigation results on a staring FMCW radar system which targets drone swarms. The parametric investigation has been carried out by using the RAPID-SIM which facilitates system-level analysis of drone swarms' radar signatures. This paper explains concepts of the simulator's each module and also covers two...

Summary report of discussion