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Bruschini, Claudio (author), Burri, Samuel (author), Bernasconi, Ermanno (author), Milanese, Tommaso (author), Ulku, Arin C. (author), Homulle, Harald (author), Charbon-Iwasaki-Charbon, E. (author)The LinoSPAD2 camera combines a 512×1 linear single-photon avalanche diode (SPAD) array with an FPGA-based photon-counting and time-stamping platform, to create a reconfigurable sensing system capable of detecting single photons. The read-out is fully parallel, where each SPAD is connected to a different FPGA input. The hardware can be...conference paper 2023
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Houwink, Quint (author), Kalisvaart, D. (author), Hung, S. (author), Cnossen, J.P. (author), Fan, D. (author), Mos, Paul (author), Ülkü, Arin Can (author), Bruschini, Claudio (author), Charbon-Iwasaki-Charbon, E. (author), Smith, C.S. (author)Single-photon avalanche diode (SPAD) arrays can be used for single-molecule localization microscopy (SMLM) because of their high frame rate and lack of readout noise. SPAD arrays have a binary frame output, which means photon arrivals should be described as a binomial process rather than a Poissonian process. Consequentially, the theoretical...journal article 2021
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Bruschini, Claudio (author), Homulle, Harald (author), Antolović, I.M. (author), Burri, S. (author), Charbon-Iwasaki-Charbon, E. (author)Single-photon avalanche diode (SPAD) arrays are solid-state detectors that offer imaging capabilities at the level of individual photons, with unparalleled photon counting and time-resolved performance. This fascinating technology has progressed at a very fast pace in the past 15 years, since its inception in standard CMOS technology in 2003....review 2019
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Antolović, I.M. (author), Bruschini, Claudio (author), Charbon-Iwasaki-Charbon, E. (author)Confocal microscopes use photomultiplier tubes and hybrid detectors due to their large dynamic range, which typically exceeds the one of single-photon avalanche diodes (SPADs). The latter, due to their photon counting operation, are usually limited to an output count rate to 1/T<sub>dead</sub>. In this paper, we present a thorough analysis,...journal article 2018
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Antolović, I.M. (author), Burri, S. (author), Bruschini, Claudio (author), Hoebe, Ron A. (author), Charbon-Iwasaki-Charbon, E. (author)sCMOS imagers are currently utilized (replacing EMCCD imagers) to increase the acquisition speed in super resolution localization microscopy. Single-photon avalanche diode (SPAD) imagers feature frame rates per bit depth comparable to or higher than sCMOS imagers, while generating microsecond 1-bit-frames without readout noise, thus paving...journal article 2017