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Straathof, R. (author), Meijaard, J.P. (author), Perez, S.M. (author), Kolkman-Deurloo, Inger Karine K. (author), Nout, Remi A. (author), Heijmen, Ben J.M. (author), Wauben, L.S.G.L. (author), Dankelman, J. (author), van de Berg, N.J. (author)Background: The steep radiation dose gradients in cervical cancer brachytherapy (BT) necessitate a thorough understanding of the behavior of afterloader source cables or needles in the curved channels of (patient-tailored) applicators. Purpose: The purpose of this study is to develop and validate computer models to simulate: (1) BT source...journal article 2024
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Perez, S.M. (author), van de Berg, N.J. (author), Manni, Francesca (author), Lai, Marco (author), Rijstenberg, Lucia (author), Hendriks, B.H.W. (author), Dankelman, J. (author), Ewing-Graham, Patricia C. (author), Nieuwenhuyzen, G.M. (author), Van Beekhuizen, Heleen J. (author)The most important prognostic factor for the survival of advanced-stage epithelial ovarian cancer (EOC) is the completeness of cytoreductive surgery (CRS). Therefore, an intraoperative technique to detect microscopic tumors would be of great value. The aim of this pilot study is to assess the feasibility of near-infrared hyperspectral imaging ...journal article 2022
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Somerwil, P.C. (author), Nout, Remi A. (author), Mens, Jan Willem M. (author), Kolkman-Deurloo, Inger Karine K. (author), Van Beekhuizen, Heleen J. (author), Dankelman, J. (author), van de Berg, N.J. (author)Brachytherapy is a common treatment in cervical, uterine and vaginal cancer management. The technique is characterised by rapid developments in the fields of medical imaging, dosimetry planning and personalised medical device design. To reduce unnecessary burden on patients, assessments and training of these technologies should preferable be...journal article 2021
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Laan, Rianne (author), Nout, Remi A. (author), Dankelman, J. (author), van de Berg, N.J. (author)Background:<br/> Brachytherapy involves placement of radioactive sources inside or near the tumour. For gynaecological cancer, recent developments, including 3D imaging and image-guided adaptive brachytherapy, have improved treatment quality and outcomes. However, for large or complex tumours, target coverage and local control with commercially...journal article 2019
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de Jong, T.L. (author), van de Berg, N.J. (author), Tas, L. (author), Moelker, Adriaan (author), Dankelman, J. (author), van den Dobbelsteen, J.J. (author)Purpose: Accurate and precise needle placement is of utmost importance in interventional radiology. However, targeting can be challenging due to, eg, tissue motion and deformation. Steerable needles are a possible solution to overcome these challenges. The present work studied the clinical need for steerable needles. We aimed to answer three...journal article 2018
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van de Berg, N.J. (author), Dankelman, J. (author), van den Dobbelsteen, J.J. (author)Purpose<br/>To study the ability of a human operator to manually correct for errors in the needle insertion path without partial withdrawal of the needle by means of an active, tip-articulated steerable needle.<br/><br/>Materials and Methods<br/>The needle is composed of a 1.32-mm outer-diameter cannula, with a flexure joint near the tip, and a...journal article 2017
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van de Berg, N.J. (author), de Jong, T.L. (author), van Gerwen, D.J. (author), Dankelman, J. (author), van den Dobbelsteen, J.J. (author)Steering of needles involves the planning and timely modifying of instrument-tissue force interactions to allow for controlled deflections during the insertion in tissue. In this work, the effect of tip shape on these forces was studied using 10 mm diameter needle tips. Six different tips were selected, including beveled and conical versions,...journal article 2017