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Malinga, L.A. (author), Abeel, T. (author), Desjardins, C.A. (author), Dlamini, T.C. (author), Cassell, G. (author), Chapman, S.B. (author), Birren, B.W. (author), Earl, A.M. (author), Van der Walt, M. (author)We report the whole-genome sequencing of two extensively drug-resistant tuberculosis strains belonging to the Euro-American S lineage. The RSA 114 strain showed single-nucleotide polymorphisms predicted to have drug efflux activity.journal article 2016
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Winglee, K. (author), McGuire, A.M. (author), Maiga, M. (author), Abeel, T.E.P.M.F. (author), Shea, T. (author), Desjardins, C.A. (author), Diarra, B. (author), Baya, B. (author), Sanogo, M. (author), Diallo, S. (author), Earl, A. (author), Bishai, W.R. (author)Background Mycobacterium africanum, made up of lineages 5 and 6 within the Mycobacterium tuberculosis complex (MTC), causes up to half of all tuberculosis cases in West Africa, but is rarely found outside of this region. The reasons for this geographical restriction remain unknown. Possible reasons include a geographically restricted animal...journal article 2016