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Coloma Hurel, J.L. (author), Lugtenburg, T.G. (author), Afendi, Muhammad (author), Lazzarotto, M. (author), Bracco Garcia, M.P. (author), Hagedoorn, P.L. (author), Gardossi, Lucia (author), Hanefeld, U. (author)Arabidopsis thaliana hydroxynitrile lyase (AtHNL) catalyzes the selective synthesis of (R)-cyanohydrins. This enzyme is unstable under acidic conditions, therefore its immobilization is necessary for the synthesis of enantiopure cyanohydrins. EziG Opal is a controlled porosity glass material for the immobilization of His-tagged enzymes. The...journal article 2020
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Haridas, M. (author), Abdelraheem, E.M.M. (author), Hanefeld, U. (author)© 2018, The Author(s). 2-Deoxy-d-ribose-5-phosphate aldolase (DERA) is a class I aldolase that offers access to several building blocks for organic synthesis. It catalyzes the stereoselective C–C bond formation between acetaldehyde and numerous other aldehydes. However, the practical application of DERA as a biocatalyst is limited by its poor...journal article 2018