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El-Habr, Elias A. (author), Dubois, Luiz G. (author), Burel-Vandenbos, Fanny (author), Bogeas, Alexandra (author), Lipecka, Joanna (author), Turchi, Laurent (author), Lejeune, François Xavier (author), Coehlo, Paulo Lucas Cerqueira (author), Yamaki, Tomohiro (author), Wittmann, Bryan M. (author), Fareh, M. (author), Mahfoudhi, Emna (author), Janin, Maxime (author), Narayanan, Ashwin (author), Morvan-Dubois, Ghislaine (author), Schmitt, Charlotte (author), Verreault, Maité (author), Oliver, Lisa (author), Sharif, Ariane (author), Pallud, Johan (author), Devaux, Bertrand (author), Puget, Stéphanie (author), Korkolopoulou, Penelope (author), Varlet, Pascale (author), Ottolenghi, Chris (author), Plo, Isabelle (author), Moura-Neto, Vivaldo (author), Virolle, Thierry (author), Chneiweiss, Hervé (author), Junier, Marie Pierre (author)
Cell populations with differing proliferative, stem-like and tumorigenic states co-exist in most tumors and especially malignant gliomas. Whether metabolic variations can drive this heterogeneity by controlling dynamic changes in cell states is unknown. Metabolite profiling of human adult glioblastoma stem-like cells upon loss of their...
journal article 2017
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Fareh, M. (author), Almairac, Fabien (author), Turchi, Laurent (author), Burel-Vandenbos, Fanny (author), Paquis, Philippe (author), Fontaine, Denys (author), Lacas-Gervais, Sandra (author), Junier, Marie Pierre (author), Chneiweiss, Hervé (author), Virolle, Thierry (author)
Glioblastomas are incurable primary brain tumors that affect patients of all ages. The aggressiveness of this cancer has been attributed in part to the persistence of treatment-resistant glioblastoma stem-like cells. We have previously discovered the tumor-suppressor properties of the microRNA cluster miR-302-367, representing a potential...
journal article 2017