Fragmenting Genome Sequences by Coding Regions to Improve Performance of the AmpliDiff Algorithm for Large Genomes

Abundance estimation with the use of environmental samples has been used during the SARS-CoV-2 pandemic to identify the abundances of different lineages. AmpliDiff, an algorithm that tries to find parts of DNA that can differentiate between different input genomes was used on a SARS-CoV-2 dataset to find these amplicons. The AmpliDiff algorithm...