Searched for: author%3A%22Rabelink%2C+Ton+J.%22
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Wang, Gangqi (author), Heijs, Bram (author), Kostidis, Sarantos (author), Rietjens, Rosalie G.J. (author), Mahfouz, A.M.E.T.A. (author), Chuva de Sousa Lopes, Susana M. (author), van den Berg, Cathelijne W. (author), van den Berg, Bernard M. (author), Rabelink, Ton J. (author)
Accumulating evidence demonstrates important roles for metabolism in cell fate determination. However, it is a challenge to assess metabolism at a spatial resolution that acknowledges both heterogeneity and cellular dynamics in its tissue microenvironment. Using a multi-omics platform to study cell-type-specific dynamics in metabolism in...
journal article 2022
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Groen, Nathalie (author), Leenders, Floris (author), Mahfouz, A.M.E.T.A. (author), Munoz-Garcia, Amadeo (author), Muraro, Mauro J. (author), de Graaf, Natascha (author), Rabelink, Ton J. (author), Hoeben, Rob (author), Reinders, M.J.T. (author)
The maintenance of pancreatic islet architecture is crucial for proper β-cell function. We previously reported that disruption of human islet integrity could result in altered β-cell identity. Here we combine β-cell lineage tracing and single-cell transcriptomics to investigate the mechanisms underlying this process in primary human islet...
journal article 2021
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Aleksinskaya, Marina A. (author), Monge, Matthieu (author), Siebelt, Michiel (author), Slot, Edith M. (author), Koekkoek, Karin M. (author), de Bruin, Ruben G. (author), Massy, Ziad A. (author), Weinans, Harrie (author), Rabelink, Ton J. (author), Fibbe, Willem E. (author), Jan van Zonneveld, Anton (author), van Pel, Melissa (author)
In chronic kidney disease (CKD), endothelial injury, is associated with disease progression and an increased risk for cardiovascular complications. Circulating cells with vascular reparative functions are hematopoietic and also reduced in CKD. To explore the mechanistic basis behind these observations, we have investigated hematopoietic stem...
journal article 2018
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van Lint, Céline (author), Wang, W. (author), van Dijk, Sandra (author), Brinkman, W.P. (author), Rövekamp, Ton J.M. (author), Neerincx, M.A. (author), Rabelink, Ton J. (author), van der Boog, Paul J.M. (author)
Background: The high frequency of outpatient visits after kidney transplantation is burdensome to both the recovering patient and health care capacity. Self-monitoring kidney function offers a promising strategy to reduce the number of these outpatient visits. Objective: The objective of this study was to investigate whether it is safe to...
journal article 2017
Searched for: author%3A%22Rabelink%2C+Ton+J.%22
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