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Vente, M.A.D. (author), Nijsen, J.F.W. (author), De Wit, T.C. (author), Seppenwoolde, J.H. (author), Krijger, G.C. (author), Seevinck, P.R. (author), Huisman, A. (author), Zonneneberg, B.A. (author), Van den Ingh, T.S.G.A.M. (author), Van het Schip, A.D. (author)Purpose The aim of this study is to evaluate the toxicity of holmium-166 poly(l-lactic acid) microspheres administered into the hepatic artery in pigs. Methods Healthy pigs (20–30 kg) were injected into the hepatic artery with holmium-165-loaded microspheres (165HoMS; n?=?5) or with holmium-166-loaded microspheres (166HoMS; n?=?13). The...journal article 2008
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Bult, W. (author), Seevinck, P.R. (author), Krijger, G.C. (author), Visser, T. (author), Kroon-Batenburg, L.M.J. (author), Bakker, C.J.G. (author), Hennink, W.E. (author), Van het Schip, A.D. (author), Nijsen, J.F.W. (author)Purpose The aim of this study was to develop microspheres with an ultra high holmium content which can be neutron activated for radioablation of malignancies. These microspheres are proposed to be delivered selectively through either intratumoral injections into solid tumors or administered via an intravascularly placed catheter. Methods...journal article
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- Vente, M.A.D. (author), De Wit, T.C. (author), Van den Bosch, M.A.A.J. (author), Bult, W. (author), Seevinck, P.R. (author), Zonnenberg, B.A. (author), De Jong, H.W.A.M. (author), Krijger, G.C. (author), Bakker, C.J.G. (author), Van Het Schip, A.D. (author), Nijsen, J.F.W. (author) journal article 2009