Cioni, Bianca (author), Nevedomskaya, Ekaterina (author), Melis, Monique H.M. (author), van Burgsteden, Johan (author), Stelloo, Suzan (author), Hodel, Emma (author), Spinozzi, Daniele (author), de Jong, Jeroen (author), Wessels, L.F.A. (author) Fibroblasts are abundantly present in the prostate tumor microenvironment (TME), including cancer-associated fibroblasts (CAFs) which play a key role in cancer development. Androgen receptor (AR) signaling is the main driver of prostate cancer (PCa) progression, and stromal cells in the TME also express AR. High-grade tumor and poor clinical...
journal article 2018
