Evaluating long-read de novo assembly tools for eukaryotic genomes: insights and considerations

Background: Assembly algorithm choice should be a deliberate, well-justified decision when researchers create genome assemblies for eukaryotic organisms from third-generation sequencing technologies. While third-generation sequencing by Oxford Nanopore Technologies (ONT) and Pacific Biosciences (PacBio) has overcome the disadvantages of short...

Simulated Design-Build-Test-Learn Cycles for Consistent Comparison of Machine Learning Methods in Metabolic Engineering

Combinatorial pathway optimization is an important tool in metabolic flux optimization. Simultaneous optimization of a large number of pathway genes often leads to combinatorial explosions. Strain optimization is therefore often performed using iterative design-build-test-learn (DBTL) cycles. The aim of these cycles is to develop a product...

NIL PROJECT "hoge sterkte staalsoorten": Eindrapport

NIL PROJECT "hoge sterkte staalsoorten: Eindrapport

De invloed van kwik op de omzetting van wit in grauw tin