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Hangel, Gilbert (author), Schmitz-Abecassis, Bárbara (author), Pinto, Joana (author), Sollmann, Nico (author), Tseng, C. (author), Vos, F.M. (author), Warnert, E.A.H. (author), Smits, M. (author), Petr, Jan (author)Preoperative clinical MRI protocols for gliomas, brain tumors with dismal outcomes due to their infiltrative properties, still rely on conventional structural MRI, which does not deliver information on tumor genotype and is limited in the delineation of diffuse gliomas. The GliMR COST action wants to raise awareness about the state of the art...review 2023
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Tseng, C. (author), Jaspers, Jaap (author), Romero, Alejandra Mendez (author), Wielopolski, Piotr (author), Smits, M. (author), van Osch, Matthias J.P. (author), Vos, F.M. (author)The arterial input function (AIF) plays a crucial role in estimating quantitative perfusion properties from dynamic susceptibility contrast (DSC) MRI. An important issue, however, is that measuring the AIF in absolute contrast-agent concentrations is challenging, due to uncertainty in relation to the measured (Formula presented.) -weighted...journal article 2023
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Nagtegaal, M.A. (author), Hermann, I. (author), Weingärtner, S.D. (author), Martinez-Heras, Eloy (author), Solana, Elisabeth (author), Llufriu, Sara (author), Gass, Achim (author), Poot, Dirk H.J. (author), van Osch, Matthias J.P. (author), Vos, F.M. (author), de Bresser, Jeroen (author)T<sub>2</sub>-hyperintense lesions are the key imaging marker of multiple sclerosis (MS). Previous studies have shown that the white matter surrounding such lesions is often also affected by MS. Our aim was to develop a new method to visualize and quantify the extent of white matter tissue changes in MS based on relaxometry properties. We...journal article 2023
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Hirschler, Lydiane (author), Sollmann, Nico (author), Schmitz-Abecassis, Bárbara (author), Pinto, Joana (author), Arzanforoosh, Fatemehsadat (author), Tseng, C. (author), Vos, F.M. (author), Warnert, E.A.H. (author), Smits, M. (author)Preoperative clinical magnetic resonance imaging (MRI) protocols for gliomas, brain tumors with dismal outcomes due to their infiltrative properties, still rely on conventional structural MRI, which does not deliver information on tumor genotype and is limited in the delineation of diffuse gliomas. The GliMR COST action wants to raise...review 2023
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Nunez-Gonzalez, L. (author), Nagtegaal, M.A. (author), Poot, D.H.J. (author), de Bresser, J. (author), van Osch, M. J.P. (author), Hernandez-Tamames, J.A. (author), Vos, F.M. (author)MR fingerprinting (MRF) is a promising method for quantitative characterization of tissues. Often, voxel-wise measurements are made, assuming a single tissue-type per voxel. Alternatively, the Sparsity Promoting Iterative Joint Non-negative least squares Multi-Component MRF method (SPIJN-MRF) facilitates tissue parameter estimation for...journal article 2022
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Karkalousos, D. (author), Noteboom, S. (author), Hulst, H. E. (author), Vos, F.M. (author), Caan, M.W.A. (author)Objective. Machine Learning methods can learn how to reconstruct magnetic resonance images (MRI) and thereby accelerate acquisition, which is of paramount importance to the clinical workflow. Physics-informed networks incorporate the forward model of accelerated MRI reconstruction in the learning process. With increasing network complexity,...journal article 2022
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Bakhshaee Babaroud, N. (author), Palmar, M. (author), Velea, A. (author), Coletti, C. (author), Weingärtner, S.D. (author), Vos, F.M. (author), Serdijn, W.A. (author), Vollebregt, S. (author), Giagka, Vasiliki (author)Multimodal platforms combining electrical neural recording and stimulation, optogenetics, optical imaging, and magnetic resonance (MRI) imaging are emerging as a promising platform to enhance the depth of characterization in neuroscientific research. Electrically conductive, optically transparent, and MRI-compatible electrodes can optimally...journal article 2022
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Heesterbeek, David G.J. (author), Koolstra, Kirsten (author), van Osch, Matthias J.P. (author), van Gijzen, M.B. (author), Vos, F.M. (author), Nagtegaal, M.A. (author)Purpose: To develop a method for MR Fingerprinting (MRF) sequence optimization that takes both the applied undersampling pattern and a realistic reference map into account. Methods: A predictive model for the undersampling error leveraging on perturbation theory was exploited to optimize the MRF flip angle sequence for improved robustness...journal article 2022
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Nagtegaal, M.A. (author), Hartsema, Emiel (author), Koolstra, Kirsten (author), Vos, F.M. (author)Purpose: To develop an efficient algorithm for multicomponent MR fingerprinting (MC-MRF) reconstructions directly from highly undersampled data without making prior assumptions about tissue relaxation times and expected number of tissues. Methods: The proposed method reconstructs MC-MRF maps from highly undersampled data by iteratively...journal article 2022
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Ambrosini, P. (author), Hollemans, Eva (author), Kweldam, Charlotte F. (author), Leenders, Geert J.L.H.van (author), Stallinga, S. (author), Vos, F.M. (author)Cribriform growth patterns in prostate carcinoma are associated with poor prognosis. We aimed to introduce a deep learning method to detect such patterns automatically. To do so, convolutional neural network was trained to detect cribriform growth patterns on 128 prostate needle biopsies. Ensemble learning taking into account other tumor...journal article 2020
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Nagtegaal, M.A. (author), Koken, Peter (author), Amthor, Thomas (author), de Bresser, Jeroen (author), Mädler, Burkhard (author), Vos, F.M. (author), Doneva, Mariya (author)Demyelination is the key pathological process in multiple sclerosis (MS). The extent of demyelination can be quantified with magnetic resonance imaging by assessing the myelin water fraction (MWF). However, long computation times and high noise sensitivity hinder the translation of MWF imaging to clinical practice. In this work, we introduce...journal article 2020
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van Valenberg, W. (author), Klein, S. (author), Vos, F.M. (author), Koolstra, Kirsten (author), van Vliet, L.J. (author), Poot, D.H.J. (author)Quantitative MRI methods that estimate multiple physical parameters simultaneously often require the fitting of a computational complex signal model defined through the Bloch equations. Repeated Bloch simulations can be avoided by matching the measured signal with a precomputed signal dictionary on a discrete parameter grid (i.e. lookup table...journal article 2020
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Bazin, Pierre Louis (author), Nijsse, Hannah E. (author), van der Zwaag, Wietske (author), Gallichan, Daniel (author), Alkemade, Anneke (author), Vos, F.M. (author), Forstmann, Birte U. (author), Caan, Matthan W.A. (author)Sub-millimeter imaging at 7T has opened new possibilities for qualitatively and quantitatively studying brain structure as it evolves throughout the life span. However, subject motion introduces image blurring on the order of magnitude of the spatial resolution and is thus detrimental to image quality. Such motion can be corrected for, but...journal article 2020
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Liebrand, Luka C. (author), van Wingen, Guido A. (author), Vos, F.M. (author), Denys, Damiaan (author), Caan, Matthan W.A. (author)Given the restricted total scanning time for clinical neuroimaging, it is unclear whether clinical diffusion MRI protocols would benefit more from higher spatial resolution or higher angular resolution. In this work, we investigated the relative benefit of improving spatial or angular resolution in diffusion MRI to separate two parallel...journal article 2020
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Arkesteijn, G.A.M. (author), Poot, D.H.J. (author), Ikram, M.A. (author), Niessen, W.J. (author), van Vliet, L.J. (author), Vernooij, M.W. (author), Vos, F.M. (author)The goal of this paper is to increase the statistical power of crossing-fiber statistics in voxelwise analyses of diffusion-weighted magnetic resonance imaging (DW-MRI) data. In the proposed framework, a fiber orientation atlas and a model complexity atlas were used to fit the ball-and-sticks model to diffusion-weighted images of subjects in...journal article 2019
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van Dongen, K.W.A. (author), de Blécourt, A.J. (author), Lens, E. (author), Schaart, D.R. (author), Vos, F.M. (author)In proton therapy high energy protons are used to irradiate a tumor. Ideally, the delivered proton dose distribution is measured during treatment to ensure patient safety and treatment effectiveness. Here we investigate if we can use the ionoacoustic wave field to monitor the actual proton dose distribution for the two most commonly used proton...journal article 2019
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Rassam, F. (author), Zhang, T. (author), Cieslak, K. P. (author), Lavini, C. (author), Stoker, J. (author), Bennink, R. J. (author), van Gulik, T. M. (author), van Vliet, L.J. (author), Runge, J. H. (author), Vos, F.M. (author)Objectives: To compare Gd-EOB-DTPA dynamic hepatocyte-specific contrast-enhanced MRI (DHCE-MRI) with <sup>99m</sup> Tc-mebrofenin hepatobiliary scintigraphy (HBS) as quantitative liver function tests for the preoperative assessment of patients undergoing liver resection. Methods: Patients undergoing liver surgery and preoperative assessment...journal article 2019
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Zhang, T. (author), Runge, Jurgen H. (author), Lavini, Cristina (author), Stoker, Jaap (author), van Gulik, Thomas (author), Cieslak, Kasia P. (author), van Vliet, L.J. (author), Vos, F.M. (author)Purpose Pharmacokinetic models facilitate assessment of properties of the micro-vascularization based on DCE-MRI data. However, accurate pharmacokinetic modeling in the liver is challenging since it has two vascular inputs and it is subject to large deformation and displacement due to respiration. Methods We propose an improved...journal article 2019
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Bouziane, Cheima (author), Filatova, O.G. (author), Schrantee, Anouk (author), Caan, Matthan W.A. (author), Vos, F.M. (author), Reneman, Liesbeth (author)Background: Methylphenidate (MPH) is highly effective in treating attention-deficit/hyperactivity disorder (ADHD). However, not much is known about its effect on the development of human brain white matter (WM). Purpose: To determine whether MPH modulates WM microstructure in an age-dependent fashion in a randomized double-blind placebo...journal article 2019
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van Schie, J.J.N. (author), Lavini, Cristina (author), van Vliet, L.J. (author), Kramer, Gem (author), Pieters - van den Bos, Indra (author), Marcus, H.J.J. (author), Stoker, Jaap (author), Vos, F.M. (author)Background: Pharmacokinetic (PK) models can describe microvascular density and integrity. An essential component of PK models is the arterial input function (AIF) representing the time-dependent concentration of contrast agent (CA) in the blood plasma supplied to a tissue. Purpose/Hypothesis: To evaluate a novel method for subject-specific...journal article 2018