- document
-
De Ronde, J.J. (author), Rigaill, G. (author), Rottenberg, S. (author), Rodenhuis, S. (author), Wessels, L.F.A. (author)Traditional methods that aim to identify biomarkers that distinguish between two groups, like Significance Analysis of Microarrays or the t-test, perform optimally when such biomarkers show homogeneous behavior within each group and differential behavior between the groups. However, in many applications, this is not the case. Instead, a subgroup...journal article 2013