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Shahzad, Rahil (author), Shankar, Arun (author), Amier, Raquel (author), Nijveldt, Robin (author), Westenberg, Jos J.M. (author), de Roos, Albert (author), Lelieveldt, B.P.F. (author), van der Geest, R.J. (author)Background: Aortic pulse wave velocity (PWV) is an indicator of aortic stiffness and is used as a predictor of adverse cardiovascular events. PWV can be non-invasively assessed using magnetic resonance imaging (MRI). PWV computation requires two components, the length of the aortic arch and the time taken for the systolic pressure wave to...journal article 2019
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Elbaz, Mohammed S.M. (author), van der Geest, Rob J. (author), Calkoen, Emmeline E. (author), de Roos, Albert (author), Lelieveldt, B.P.F. (author), Roest, Arno A.W. (author), Westenberg, Jos J.M. (author)Purpose To evaluate viscous energy loss and the association with three-dimensional (3D) vortex ring formation in left ventricular (LV) blood flow during diastolic filling. Theory and Methods Thirty healthy volunteers were compared with 32 patients with corrected atrioventricular septal defect as unnatural mitral valve morphology and inflow are...journal article 2017
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Leeuwis, Anna E. (author), Hooghiemstra, Astrid M. (author), Amier, Raquel (author), Ferro, Doeschka A. (author), Franken, Leonie (author), Nijveldt, Robin (author), Kuijer, Joost P A (author), Bronzwaer, Anne Sophie G T (author), van Lieshout, Johannes J. (author), Rietberg, Marc B. (author), Veerbeek, Janne M. (author), Huijsmans, Rosalie J. (author), Backx, Frank J G (author), Teunissen, Charlotte E. (author), Bron, Esther E. (author), Barkhof, Frederik (author), Prins, Niels D. (author), Shahzad, Rahil (author), Niessen, W.J. (author), de Roos, Albert (author), van Osch, Matthias J P (author), van Rossum, Albert C. (author), Biessels, Geert J. (author), van der Flier, Wiesje M. (author)There is evidence for a beneficial effect of aerobic exercise on cognition, but underlying mechanisms are unclear. In this study, we test the hypothesis that aerobic exercise increases cerebral blood flow (CBF) in patients with vascular cognitive impairment (VCI). This study is a multicenter single-blind randomized controlled trial among 80...journal article 2017
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Hooghiemstra, Astrid M. (author), Bertens, Anne Suzanne (author), Leeuwis, Anna E. (author), Bron, Esther E. (author), Bots, Michiel L. (author), Brunner-La Rocca, Hans Peter (author), De Craen, Anton J M (author), van der Geest, Rob J. (author), Greving, Jacoba P. (author), Kappelle, L. Jaap (author), Niessen, W.J. (author), van Oostenbrugge, Robert J. (author), van Osch, Matthias J P (author), de Roos, Albert (author), van Rossum, Albert C. (author), Biessels, Geert Jan (author), van Buchem, Mark A. (author), Daemen, Mat J A P (author), van der Flier, Wiesje M. (author)Background: Hemodynamic balance in the heart-brain axis is increasingly recognized as a crucial factor in maintaining functional and structural integrity of the brain and thereby cognitive functioning. Patients with heart failure (HF), carotid occlusive disease (COD), and vascular cognitive impairment (VCI) present themselves with complaints...journal article 2017