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Arbabi, Saeed (author), Foppen, Wouter (author), Gielis, Willem Paul (author), van Stralen, Marijn (author), Jansen, Mylène (author), Arbabi, Vahid (author), de Jong, Pim A. (author), Weinans, Harrie (author), Seevinck, Peter (author)Magnetic resonance Imaging is the gold standard for assessment of soft tissues; however, X-ray-based techniques are required for evaluating bone-related pathologies. This study evaluated the performance of synthetic computed tomography (sCT), a novel MRI-based bone visualization technique, compared with CT, for the scoring of knee...journal article 2023
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Kuperus, J.S. (author), Smit, E.J.M. (author), Pouran, B. (author), van Hamersvelt, R.W. (author), van Stralen, Marijn (author), Seevinck, P.R. (author), Buckens, C.F. (author), Bleys, Ronald L.A.W. (author), Weinans, Harrie (author), Oner, F. C. (author), de Jong, P.A. (author), Verlaan, J-J (author)Diffuse idiopathic skeletal hyperostosis (DISH) is often theorized to be an ossification of the anterior longitudinal ligament (ALL). Using computed tomography (CT) imaging and cryomacrotome sectioning, we investigated the spatial relationship between the ALL and newly formed bone in DISH to test this hypothesis. In the current study, four...journal article 2018
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Weeber, Fleur (author), Cirkel, Geert A. (author), Hoogstraat, Marlous (author), Bins, Sander (author), Gadellaa-van Hooijdonk, Christa G.M. (author), Ooft, Salo (author), van Werkhoven, Erik (author), Willems, Stefan M. (author), van Stralen, Marijn (author), Veldhuis, Wouter B. (author), Besselink, Nicolle J.M. (author), Horlings, Hugo M. (author), Steeghs, Neeltje (author), de Jonge, Maja J. (author), Langenberg, Marlies H.G. (author), Wessels, L.F.A. (author), Cuppen, Edwin (author), Cuppen, Edwin (author), Schellens, J.H. (author), Sleijfer, Stefan (author), Lolkema, Martijn P. (author), Voest, Emile E. (author)Background: In this study, our aim was to identify molecular aberrations predictive for response to everolimus, an mTOR inhibitor, regardless of tumor type. Methods: To generate hypotheses about potential markers for sensitivity to mTOR inhibition, drug sensitivity and genomic profiles of 835 cell lines were analyzed. Subsequently, a...journal article 2017