Martins Costa, A.R. (author), van den Berg, D.F. (author), Esser, J.Q. (author), Muralidharan, A. (author), van den Bossche, Halewijn (author), Estrada Bonilla, B.A. (author), van der Steen, B.A. (author), Haas, Pieter Jan (author), Brouns, S.J.J. (author) Prokaryotes encode multiple distinct anti-phage defense systems in their genomes. However, the impact of carrying a multitude of defense systems on phage resistance remains unclear, especially in a clinical context. Using a collection of antibiotic-resistant clinical strains of Pseudomonas aeruginosa and a broad panel of phages, we...
journal article 2024
