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Breitwieser, Lukas (author), Hesam, A.S. (author), De Montigny, Jean (author), Vavourakis, Vasileios (author), Iosif, Alexandros (author), Jennings, Jack (author), Kaiser, Marcus (author), Manca, Marco (author), Di Meglio, Alberto (author), Al-Ars, Z. (author), Rademakers, Fons (author), Mutlu, Onur (author), Bauer, Roman (author)Motivation: Agent-based modeling is an indispensable tool for studying complex biological systems. However, existing simulation platforms do not always take full advantage of modern hardware and often have a field-specific software design. Results: We present a novel simulation platform called BioDynaMo that alleviates both of these problems....journal article 2022
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Fraser, Alan (author), Nelissen, R.G.H.H. (author), Kjærsgaard-Andersen, P. (author), Szymański, P. (author), Melvin, T. (author), Piscoi, P. (author), Fraser, Alan (author), Szymański, Piotr (author), Gale, Chris (author), Maggioni, Aldo (author), Zanon, Elisabetta (author), Dimopoulou, Christina (author), Ceccarelli, Cinzia (author), Vairami, Polyxeni (author), Ruszanov, Anett (author), Kjærsgaard-Andersen, Per (author), Nelissen, Rob (author), Ott, Adrian (author), Macintyre, Elizabeth (author), Simulescu, Loredana (author), Meijer, Marieke (author), Koletzko, Berthold (author), Wieczorek, Sarah (author), Hadjipanayis, Adamos (author), Del Torso, Stefano (author), Marang-van de Mheen, P.J. (author), Hoogervorst, L. (author), Steyerberg, Ewout W. (author), de Vries, B. (author), McCulloch, Peter (author), Landray, Martin (author), Alhambra, Daniel Prieto (author), Smith, James (author), Lubbeke-Wolf, Anne (author), James, Stefan (author), Buccheri, Sergio (author), Byrne, Robert (author), McGovern, Laurna (author), Windecker, Stephan (author), Frenk, Andre (author), Siontis, Georgios (author), Stettler, Christoph (author), Bano, Arjola (author), Bally, Lia (author), Rademakers, Frank E. (author), D'hooge, Jan (author), Vedder, Anton (author), Biasin, Elisabetta (author), Kamenjasevic, Erik (author), Schnell-Inderst, Petra (author)In the European Union (EU) the delivery of health services is a national responsibility but there are concerted actions between member states to protect public health. Approval of pharmaceutical products is the responsibility of the European Medicines Agency, whereas authorizing the placing on the market of medical devices is decentralized to...journal article 2022
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Drijkoningen, G.G. (author), Rademakers, F. (author), Slob, E.C. (author), Fokkema, J.T. (author)Ground coupling are terms that describe the transfer from seismic ground motion to the motion of a geophone. In previous models, ground coupling was mainly considered as a disk lying on top of a half-space, not considering the fact that in current practice geophones are spiked and are buried for optimal response. In this paper we introduce a new...journal article 2006